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Genome Editing in Cardiovascular and Metabolic Diseases

  • Book
  • © 2023

Overview

Editors:
  1. Junjie Xiao

    1. Institute of Cardiovascular Sciences, Shanghai Engineering Research Center of Organ Repair, School of Life Science, Shanghai University, Shanghai, China

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  • Focuses on the cutting-edge research on genome editing in cardiovascular and metabolic diseases
  • Includes bioinformatics research methodology of genome editing in cardiovascular and metabolic diseases
  • Highlights the study of genome editing and their therapeutic implications

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1396)

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Table of contents (20 chapters)

  1. Front Matter

    Pages i-xii
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  3. Bioinformatics

    1. Front Matter

      Pages 17-17
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    2. Online Databases of Genome Editing in Cardiovascular and Metabolic Diseases

      • Paula Carrillo-Rodriguez, Javier Martinez-Lopez, Laura Gómez-Hernández, Luis Boraita-Morales, Maria Uceda-Molina, Irene Cuenca-Bermejo et al.
      Pages 19-33

  4. Genome Editing in Cardiovascular Disease

    1. Front Matter

      Pages 35-35
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    2. Genome Editing and Cardiac Regeneration

      • Rayhaan Bassawon, Kashif Khan, Ateeque Siddique, Dominique Shum-Tim
      Pages 37-52

    3. Genome Editing and Myocardial Development

      • Sifa Turan, J. Richard Chaillet, Margaret C. Stapleton, Yijen L. Wu
      Pages 53-73

    4. Genome Editing and Heart Failure

      • Daniele Masarone, Martina Caiazza, Federica Amodio, Enrico Melillo, Roberta Pacileo, Giuseppe Limongelli et al.
      Pages 75-85

    5. Genome Editing and Pathological Cardiac Hypertrophy

      • Takao Kato
      Pages 87-101

    6. Genome Editing and Diabetic Cardiomyopathy

      • Tyler N. Kambis, Paras K. Mishra
      Pages 103-114

    7. Genome Editing and Inherited Cardiac Arrhythmias

      • Laura Lalaguna, Laura Ramos-Hernández, Silvia G. Priori, Enrique Lara-Pezzi
      Pages 115-127

    8. Genome Editing and Atrial Fibrillation

      • Michael Spartalis
      Pages 129-137

    9. Genome Editing in Dyslipidemia and Atherosclerosis

      • Zhifen Chen, Constanze Lehertshuber, Heribert Schunkert
      Pages 139-156

    10. Genome Editing to Abrogate Muscle Atrophy

      • Tingting Yang, Priyanka Gokulnath, Xinxiu Meng, Guoping Li, Junjie Xiao
      Pages 157-176

  5. Genome Editing in Metabolic Diseases

    1. Front Matter

      Pages 177-177
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    2. Genome Editing and Obesity

      • Davide Masi, Rossella Tozzi, Mikiko Watanabe
      Pages 179-190

    3. Genome Editing and Fatty Liver

      • Umar Hayat, Ali A. Siddiqui, Muhammad L. Farhan, Ahmed Haris, Nasir Hameed
      Pages 191-206

    4. Genomic Editing and Diabetes

      • Parth Shah
      Pages 207-214

    5. Genome Editing and Protein Energy Malnutrition

      • Sergio Moreno-Nombela, Javier Romero-Parra, Francisco Javier Ruiz-Ojeda, Patricio Solis-Urra, Aiman Tariq Baig, Julio Plaza-Diaz
      Pages 215-232
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Keywords

About this book

This book provides the latest research progress on genome editing in cardiovascular and metabolic diseases and includes bioinformatics research methodology of genome editing. Genome editing is a genetic engineering technique precisely modified specific target genes of organism genome, which has been applied to basic theoretical research and production applications from plants and animals to gene therapy of human beings. Cardiovascular and metabolic diseases have become major factors affecting human health worldwide. This book contains information about bioinformatics, genome editing in cardiovascular diseases, genome editing in metabolic diseases and therapeutic effects. It will be useful for biologist, cardiologist, cardiovascular surgeons, endocrinologist, internists, nurses, undergraduate and graduate students in medicine and cell biology and others interested in cardiovascular and metabolic medicine.

Editors and Affiliations

  • Institute of Cardiovascular Sciences, Shanghai Engineering Research Center of Organ Repair, School of Life Science, Shanghai University, Shanghai, China

    Junjie Xiao

About the editor

Dr. Junjie Xiao is the Vice Dean of the School of Life Science and also of the Medical School at Shanghai University. He is the Associate Editor of the Journal of Cardiovascular Translational Research, BMC Sports and Science, Medicine& Rehabilitation, and a member of the editorial board of BMC Medicine. He is the author or co-author of numerous scientific articles in various journals, including Cell Metabolism, Nature Communications, Annual Review of Genomics and Human Genetics, Circulation, and Theranostics. His major research interest is exercise and myocardial protection, especially using exercise as a platform to identify novel targets for enhancing cardiac regeneration and combating heart failure.

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