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Innovation in Life Sciences

The Digital Revolution

  • Book
  • © 2024

Overview

Editors:
  1. Avo Schönbohm

    1. Berlin School of Economics and Law, Berlin, Germany

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  2. Hans Henning von Horsten

    1. HTW Berlin - University of Applied Sciences, Berlin, Germany

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  3. Philipp Plugmann

    1. SRH University of Applied Health Science, Leverkusen, Germany

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  4. Moritz von Stosch

    1. DataHow AG, Dübendorf, Switzerland

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  • Presents interdisciplinary insights into the digitalisation of the life science industry
  • Includes in-depth case studies of digital disruption
  • Discusses future business models for digital healthcare

Part of the book series: Management for Professionals (MANAGPROF)

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Table of contents (15 chapters)

  1. Front Matter

    Pages i-xii
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  2. The Future Is Now and Digital

    1. Front Matter

      Pages 1-1
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    2. Dancing with Biopunks: Innovation in the Life Science Industry and Science Fiction

      • Avo Schönbohm, Isabella Hermann
      Pages 3-14

    3. Artificial Intelligence Is a Game Changer in Drug Discovery R&D

      • Timofei Ermak
      Pages 15-29

    4. Digitally Enhanced Life Cycle Management for a Blockbuster Prescription Drug

      • Matthias Mahn, Henning Witt
      Pages 31-44

    5. Artificial Intelligence Applications for Producing Glycosylated Biopharmaceutical Drug Modalities

      • Hans Henning von Horsten
      Pages 45-59

    6. Digital Process Development and Manufacturing of Biopharmaceuticals: Is It a Revolution?

      • Moritz von Stosch
      Pages 61-75

    7. Rethinking Data Acquisition to Data Analytics in Bioprocessing

      • Sophia Bongard, Nicole Kees, Pedro Ivo Guimarães, Tobias Großkopf
      Pages 77-93

  3. Digital Healthcare

    1. Front Matter

      Pages 95-95
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    2. Patient-Specific Treatment in Hand Surgery: Smart Innovations and Rapid Translation into the Point of Care

      • Philipp Honigmann, Florian M. Thieringer, Neha Sharma, Marco Keller
      Pages 97-121

    3. Wish or Truth: Can Digital Interventions Stop the Obesity Crisis?

      • Dorothea Portius
      Pages 123-147

    4. Artificial Intelligence in Musculoskeletal Medical Imaging

      • Marco Keller, Florian M. Thieringer, Philipp Honigmann
      Pages 149-168

  4. Managing Innovation

    1. Front Matter

      Pages 169-169
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    2. Startup Ecosystem Around Digital Life Sciences

      • Rafaela Kunz, Karl-Florian Platt
      Pages 171-189

    3. Strategic Management for Innovation in Life Sciences: A Comprehensive Overview

      • Soham Saha, Victor Hannothiaux, Manish Sarkar, Sophie Ameloot
      Pages 191-212

    4. How to Design a Modern Medical Records System

      • Annegret Junker
      Pages 213-227

    5. Harnessing the Power of Games for Innovation in the Life Sciences

      • Avo Schönbohm, Tanawat Vongsurbchart, Kan Teerasatienspon
      Pages 229-242

    6. Digitalization Is About Managing Change: Thoughts and Learning from the Life Science Industry

      • Rita Lencastre, Watson Neto
      Pages 243-260

    7. Academics’ Willingness to Participate in an Open Innovation Healthcare and Life Science Ecosystem Platform Outside Their Qualifications and Working Experience (Follow-Up Study)

      • Philipp Plugmann
      Pages 261-272
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Keywords

About this book

The Life Science industry has been subject to a digital revolution upending all facets of the value chain with data-driven approaches like Gene Therapy, Personalized Medicine, Advanced Cell and Tissue Engineering, Industry 4.0, Artificial Intelligence, Blockchain, Digital Twins, Internet-of-Medical-Things (IoMT) and Software-as-a-Medical-Device (SaMD). Our edited volume offers comprehensive coverage of the digital disruption sweeping through the industry. From drug discovery to manufacturing and life-cycle management, we explore the profound impact of digitalization. Our authors delve into open innovation, sci-fi prototyping, and the digital transformation of medical imaging and healthcare. This volume goes beyond theory to provide practical insights. We present business-oriented case studies, examine M&A topics, venture capital, and other investor perspectives, all with a strong focus on digitalization's role. Furthermore, we explore the cultural and ethical challenges that arise andthe necessary management changes demanded by this digital revolution.

Editors and Affiliations

  • Berlin School of Economics and Law, Berlin, Germany

    Avo Schönbohm

  • HTW Berlin - University of Applied Sciences, Berlin, Germany

    Hans Henning von Horsten

  • SRH University of Applied Health Science, Leverkusen, Germany

    Philipp Plugmann

  • DataHow AG, Dübendorf, Switzerland

    Moritz von Stosch

About the editors

Avo Schönbohm is Professor for Business Administration at the Berlin School of Economics and Law / HWR Berlin (Germany) since 2010. His international research expertise lies in the areas of (strategic) performance management, enterprise gamification and digital transformation. He has authored more than 50 publications. International teaching assignments in Vietnam, Poland, France and Switzerland have enriched his teaching style and academic horizon. Prior to joining the HWR Berlin, Avo held various international roles in the machine tool industry, ending his pre-academic career as Vice President Strategic Planning at Voith Paper GmbH with 2bn € sales in 2010. With LUDEO he created a business agency in 2016 to bring game thinking into business life and thus enhance behaviour and performance of organisations in a variety of industries.

Hans Henning von Horsten is a Professor for Industrial Biomanufacturing at HTW-Berlin-University of Applied Sciences (Germany) and Founding Dean of theFaculty of Pharmaceutical Engineering and Technology at the German International University of Applied Sciences in Cairo (Egypt) . Currently, he is serving as the deputy manager for the Life Science Management study program at HTW Berlin. Prior to joining HTW-Berlin he was in charge of project and technology management within the Cell Line Development Business Unit of ProBioGen AG, an internationally operating Contract Development and Manufacturing Organization (CDMO) for the biopharmaceutical industry. In this role, he was among the key inventors of ProBioGen’s GlymaxX antibody engineering technology that was outlicensed to Boehringer-Ingelheim, Novartis, Thermo-Fisher Scientific, Bayer, Roche, Abbvie and several other drug developers. He is co-inventor of several patents for the biomanufacturing business.

Philipp Plugmann has been doing multidisciplinary work for the last 20 years in parallel to practicing as a dentist in his own clinic in Leverkusen (Germany). He is also Full Professor for Interdisciplinary Periodontology and Prevention at SRH University of Applied Health Sciences. His first book on innovation in medical technology published in 2011 was reviewed by Cisco. His second book on innovation published with Springer in 2018 got more than 50,000 chapter downloads in its first fifteen months. Previously, he held multiple adjunct faculty appointments for more than twelve years and has won multiple teaching awards. He also holds an MBA, a MSc in Business Innovation, a MSc in Periodontology and Implant Therapy (DGParo) and is currently pursuing his third doctorate. Plugmann has given research talks in the field of innovation at Conferences at Harvard Business School, Berkeley Haas School of Business, Max Planck Institute for Innovation and Competition, and Nanyang Tech University, Singapore. Philipp Plugmann is a serial entrepreneur and advisor to several companies, including a global technology consultancy - DataArt.

Moritz von Stosch is a thought leader in the area of hybrid modeling for bioprocess development and manufacturing. He is the co-author of more than 40 scientific publications, including the Book “Hybrid Modelling in Process Industries”. He is the Chief Innovation Officer at DataHow AG and Managing Director of DataHow LDA (Switzerland). Prior to joining DataHow, Moritz led the Process Systems Biology & Engineering Centre of Excellence at GSK Vaccines, for which he received an Innovation Performance and Trust award and was nominated a change catalyst. He lectured at Newcastle University (England), holds a PhD in Biochemical Engineering from University of Porto (Portugal) and received a Dipl.Ing. in Chemical Engineering from RWTH Aachen University (Germany).

Bibliographic Information

  • Book Title: Innovation in Life Sciences

  • Book Subtitle: The Digital Revolution

  • Editors: Avo Schönbohm, Hans Henning von Horsten, Philipp Plugmann, Moritz von Stosch

  • Series Title: Management for Professionals

  • DOI: https://doi.org/10.1007/978-3-031-47768-3

  • Publisher: Springer Cham

  • eBook Packages: Business and Management, Business and Management (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2024

  • Hardcover ISBN: 978-3-031-47767-6Published: 05 April 2024

  • Softcover ISBN: 978-3-031-47770-6Due: 12 May 2024

  • eBook ISBN: 978-3-031-47768-3Published: 04 April 2024

  • Series ISSN: 2192-8096

  • Series E-ISSN: 2192-810X

  • Edition Number: 1

  • Number of Pages: XII, 272

  • Number of Illustrations: 16 b/w illustrations, 92 illustrations in colour

  • Topics: Business and Management, general, Health Care Management, Health Economics, Industries

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