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Phase-Separated Biomolecular Condensates

Editors:

(view affiliations)
  • Includes cutting-edge methods and protocols

  • Provides step-by-step detail essential for reproducible results

  • Contains key notes and implementation advice from the experts

Part of the book series: Methods in Molecular Biology (MIMB, volume 2563)

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About this book

This volume provides readers with a broad collection of theoretical, computational, and experimental methods to quantitatively study the properties of phase-separate biomolecular condensates in diverse systems. The chapters in this book cover topics such as theoretical and computational methods; methods for in vitro characterization of biomolecular condensates; and techniques that enable in-cell characterization of biomolecular condensates. Written in the highly successful Methods in Molecular Biology series format, chapters include introduction to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and expert tips on troubleshooting and avoiding known pitfalls.

Comprehensive and thorough, Phase-Separated Biomolecular Condensates: Methods and Protocols is a valuable resource that helps researchers learn and use established methods to study both biophysical properties and biological functions of biomolecular condensates. 


Keywords

  • thermodynamics
  • phase equilibrium
  • phase separation
  • High-throughput screening
  • NMR

Editors and Affiliations

  • Department of Chemistry, University of Illinois at Chicago, Chicago, USA

    Huan-Xiang Zhou

  • Department of Physics, University of Illinois at Chicago, Chicago, USA

    Jan-Hendrik Spille

  • Department of Physics, University at Buffalo, State University, Buffalo, USA

    Priya Banerjee

Bibliographic Information

  • Book Title: Phase-Separated Biomolecular Condensates

  • Editors: Huan-Xiang Zhou, Jan-Hendrik Spille, Priya Banerjee

  • Series Title: Methods in Molecular Biology

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2022

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 1

  • Number of Pages: XII, 438

  • Number of Illustrations: 6 b/w illustrations, 113 illustrations in colour

  • Topics: Biochemistry, Computational and Systems Biology

Buying options

Hardcover Book
USD 249.99
Price excludes VAT (USA)
This title has not yet been released. You will be able to pre-order it soon.