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Epidermal Growth Factor

Methods and Protocols

  • Tarun B. Patel
  • Paul J. Bertics

Part of the Methods in Molecular Biology book series (MIMB, volume 327)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Francis Edwin, Gregory J. Wiepz, Rakesh Singh, Chimera Rene Peet, Deepti Chaturvedi, Paul J. Bertics et al.
    Pages 1-24
  3. Gregory J. Wiepz, Arturo G. Guadaramma, David L. Fulgham, Paul J. Bertics
    Pages 25-38
  4. Jacqueline M. Lafky, Andre T. Baron, Nita J. Maihle
    Pages 39-47
  5. Esther Sook Miin Wong, Graeme R. Guy
    Pages 61-83
  6. Oliver M. Fischer, Stefan Hart, Axel Ullrich
    Pages 85-97
  7. Umut Sahin, Gisela Weskamp, Yufang Zheng, Valerie Chesneau, Keisuke Horiuchi, Carl P. Blobel
    Pages 99-113
  8. Menachem Katz, Yaron Mosesson, Yosef Yarden
    Pages 115-129
  9. Mirko H. H. Schmidt, Ivan Dikic
    Pages 131-138
  10. Reema Zeineldin, Laurie G. Hudson
    Pages 147-158
  11. Alan Wells, Brian Harms, Akihiro Iwabu, Lily Koo, Kirsty Smith, Linda Griffith et al.
    Pages 159-177
  12. Gregory J. Wiepz, Francis Edwin, Tarun Patel, Paul J. Bertics
    Pages 179-187
  13. Prakash Chinnaiyan, Paul M. Harari
    Pages 189-202
  14. Back Matter
    Pages 203-209

About this book

Introduction

Epidermal growth factor (EGF) and related molecules regulate a wide array of biological events, ranging from normal growth and development to such pathological states as cancer and cardiovascular diseases. In Epidermal Growth Factor: Methods and Protocols, expert researchers active in the field present their best methods to dissect the mechanisms that control growth factors and their regulators in both normal and pathological states. These readily reproducible techniques range from the study of purified EGF receptor to complex signaling and processing networks in intact cells, including a chapter on the clinical and pharmacological considerations of their use in cancer therapy. The protocols follow the successful Methods in Molecular Biology™ series format, each offering step-by-step laboratory instructions, an introduction outlining the principles behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.
Cutting-edge and highly practical, Epidermal Growth Factor: Methods and Protocols offers investigators an array of powerful and proven tools to unravel the workings of epidermal growth factor, as well as develop new strategies for the successful use of this important developmental and therapeutic target.

Keywords

Activation Migration PCR Vivo adenylyl cyclase molecular biology reproducible techniques

Editors and affiliations

  • Tarun B. Patel
    • 1
  • Paul J. Bertics
    • 2
  1. 1.Department of Pharmacology and Experimental TherapeuticsLoyola University ChicagoMaywood
  2. 2.Department of Biomolecular ChemistryUniversity of WisconsinMadison

Bibliographic information

  • DOI https://doi.org/10.1385/159745012X
  • Copyright Information Humana Press 2006
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-58829-421-0
  • Online ISBN 978-1-59745-012-6
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site