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  • Book
  • © 2003

Cytokines and Colony Stimulating Factors

Methods and Protocols

Editors:

  1. Dieter Körholz

    1. Department of Pediatrics, University of Leipzig, Leipzig, Germany

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. Wieland Kiess

    1. Department of Pediatrics, University of Leipzig, Leipzig, Germany

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Methods in Molecular Biology (MIMB, volume 215)

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Table of contents (35 protocols)

  1. Detection Assays for Cytokines and Growth Factors

    2. Gene Transfer to Articular Chondrocytes with Recombinant Adenovirus

      • Glyn D. Palmer, Elvire Gouze, Jean-Noel Gouze, Oliver B. Betz, Christopher H. Evans, Steven C. Ghivizzani
      Pages 235-246

    3. Gene Therapy of X-Linked Severe Combined Immunodeficiency

      • Salima Hacein-Bey-Abina, Genevieve de Saint Basile, Marina Cavazzana-Calvo
      Pages 247-259

    4. Gene Transfer for Generation of Tumor and Leukemia Vaccines

      • Dagmar Dilloo, Andree Zibert
      Pages 261-277

    5. Cytokine Gene Delivery into the Central Nervous System Using Intrathecally Injected Nonreplicative Viral Vectors

      • Roberto Furlan, Stefano Pluchino, Peggy C. Marconi, Gianvito Martino
      Pages 279-289

  2. Ex Vivo Cell Expansion

    1. Front Matter

      Pages 291-291
      PDF

    3. In Vitro Generation of Dendritic Cells from Cord Blood CD34+Hematopoietic Progenitors Cells

      • Bruno Canque, Michele Rosenzwajg, Jean Claude Gluckman
      Pages 311-325

    4. Generation of TransgenicT Cells from Human CD34+Cord Blood Cells

      • Bruno Verhasselt, Evelien Naessens, Veronique Stove
      Pages 327-339

    7. 27 Ex Vivo Expansion of Hematopoietic Stem Cells

      • Beatriz Albella, José Carlos Segovia, Guillermo Guenechea, Juan Antonio Bueren
      Pages 363-373

    9. Cytokine-Mediated Expansion of Human NOD-SCID-Repopulating Cells

      • Kohichiro Tsuji, Takahiro Ueda, Yasuhiro Ebihara
      Pages 387-395

  3. Maturation and Differentiation of Dendritic Cells

    1. Front Matter

      Pages 397-397
      PDF

    3. Dendritic Cell Development from Mobilized Peripheral Blood CD34+Cells

      • Deanne M. R. Lathers, Nicholas Achille, M. Rita I. Young
      Pages 409-416

    4. In Vitro Maturation of Dendritic Cells from Blood Progenitors

      • Lina Matera, Alessandra Galetto
      Pages 417-426

    5. Generation of Human Type 1- and Type 2-Polarized Dendritic Cells from Peripheral Blood

      • Pawel Kalinski, Pedro Vieira, Joost H. N. Schuitemaker, Quan Cai, Martien Kapsenberg
      Pages 427-436
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About this book

The immune system is a complex network in which different cell types and soluble factors interact to efficiently eliminate various kinds of microorganisms as well as aberrant cell clones. The roots of immunologic investigations reach far into the past. In 430 BC, Thucydides reported that survivors of the plague did not present a second time with similar symptoms. The first report of a successful immu- therapy was made by Edward Jenner in 1798 who found a protective effect of cowpox vaccination against human pox. Since then, much knowledge has been accumulated; today, investigations of the molecular mechanisms of immune regulation are of central research interest. The novel insights into gene polymorphisms and gene regulation gathered from this work has improved our knowledge of individual immune reactions and risk factors in overcoming infections. Strategies to use the immune system for cancer treatment have been propelled by the discovery of divergent immunoregulatory cytokines and the introduction of new gene therapy strategies to modify immune responses. Recently, the discovery of various dendritic cells has focused attention on these cell types as central elements of the immune response and to the possibility of dendritic cell expansion, maturation, and consecutive stimulation with immuno- active tumor-specific peptides. Similarly, methods for ex vivo expansion of various stem cell-derived cell types have led to an improved therapeutic management of various benign and malignant diseases.
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Editors and Affiliations

  • Department of Pediatrics, University of Leipzig, Leipzig, Germany

    Dieter Körholz, Wieland Kiess

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Bibliographic Information

  • Book Title: Cytokines and Colony Stimulating Factors

  • Book Subtitle: Methods and Protocols

  • Editors: Dieter Körholz, Wieland Kiess

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1385/1592593453

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Humana Press 2003

  • Hardcover ISBN: 978-1-58829-035-9Published: 08 November 2002

  • Softcover ISBN: 978-1-61737-318-3Published: 10 November 2010

  • eBook ISBN: 978-1-59259-345-3Published: 04 February 2008

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 1

  • Number of Pages: XV, 478

  • Topics: Immunology

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Buy it now

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

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