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Combinatorial Peptide Library Protocols

  • Shmuel Cabilly

Part of the Methods in Molecular Biology™ book series (MIMB, volume 87)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Colette T. Dooley, Richard A. Houghten
    Pages 13-24
  3. John M. Ostresh, Barbara Dörner, Richard A. Houghten
    Pages 41-49
  4. Channa K. Jayawickreme, Shiranthi P. Jayawickreme, Michael R. Lerner
    Pages 107-118
  5. Channa K. Jayawickreme, Shiranthi P. Jayawickreme, Michael R. Lerner
    Pages 119-128
  6. Baruch Stern, Jonathan M. Gershoni
    Pages 137-154
  7. Shmuel Cabilly, Judith Heldman, Eliahu Heldman, Ephraim Katchalski-Katzir
    Pages 175-183
  8. Shmuel Cabilly, Judith Heidman, Ephraim Katchalski-Katzir
    Pages 185-194
  9. Antonella Folgori, Alessandra Luzzago, Paolo Monaci, Alfredo Nicosia, Riccardo Cortese, Franco Felici
    Pages 195-208
  10. J. Estaquier, J.-C. Ameisen, C. Auriault, C. Boutillon, H. Gras-Masse, A. Tartar
    Pages 281-296
  11. Back Matter
    Pages 297-313

About this book

Introduction

Shmuel Cabilly presents in Combinatorial Peptide Library Protocols a collection of new and unique techniques for the construction and use of peptide libraries. These powerful methods-often detailed here by their pioneers-include protocols for the chemical synthesis of peptide libraries, for constructing peptide libraries that are displayed on the surface of filamentous phage or bacteria, and for the rapid screening of these libraries for molecules with biospecific properties. Additional methods permit identifying specific enzyme substrates, investigating the recognition spectra of various binding proteins, epitope mapping, and identifying mimotopes.

Combinatorial Peptide Library Protocols offers novice and experienced investigators alike the ability to select molecules from a randomized pool having specific biological activities. Its state-of-the-art techniques, combined with clear step-by-step instructions, make this book an essential tool in the selection of peptides suitable for drug development.

Editors and affiliations

  • Shmuel Cabilly
    • 1
  1. 1.Weizmann Institute of ScienceRehovotIsrael

Bibliographic information

  • DOI https://doi.org/10.1385/0896033929
  • Copyright Information Humana Press 1998
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-0-89603-392-4
  • Online ISBN 978-1-59259-571-6
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site