Computer Analysis of Sequence Data

Part I

  • Annette M. Griffin
  • Hugh G. Griffin

Part of the Methods in Molecular Biology book series (MIMB, volume 24)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Hugh G. Griffin, Annette M. Griffin
    Pages 1-8
  3. Reinhard Dölz
    Pages 9-23
  4. Reinhard Dölz
    Pages 25-33
  5. Reinhard Dölz
    Pages 35-46
  6. Reinhard Dölz
    Pages 65-82
  7. Reinhard Dölz
    Pages 101-116
  8. Reinhard Dölz
    Pages 117-127
  9. Reinhard Dölz
    Pages 129-142
  10. Reinhard Dölz
    Pages 143-157
  11. Reinhard Dölz
    Pages 159-166
  12. Reinhard Dölz
    Pages 167-171
  13. P. Davies, R. K. Merrifield
    Pages 201-215
  14. R. K. Merrifield
    Pages 217-225
  15. R. K. Merrifield
    Pages 227-235
  16. R. K. Merrifield
    Pages 237-258

About this book

Introduction

DNA sequencing has become increasingly efficient over the years, resulting in an enormous increase in the amount of data gen- ated. In recent years, the focus of sequencing has shifted, from being the endpoint of a project, to being a starting point. This is especially true for such major initiatives as the human genome project, where vast tracts of DNA of unknown function are sequenced. This sheer volume of available data makes advanced computer methods ess- tial to analysis, and a familiarity with computers and sequence ana- sis software a vital requirement for the researcher involved with DNA sequencing. Even for nonsequencers, a familiarity with sequence analysis software can be important. For instance, gene sequences already present in the databases can be extremely useful in the design of cloning and genetic manipulation experiments. This two-part work on Analysis of Data is designed to be a practical aid to the researcher who uses computers for the acquisition, storage, or analysis of nucleic acid (and/or p- tein) sequences. Each chapter is written such that a competent sci- tist with basic computer literacy can carry out the procedure successfully at the first attempt by simply following the detailed pr- tical instructions that have been described by the author. A Notes section, which is included at the end of each chapter, provides advice on overcoming the common problems and pitfalls sometimes enco- tered by users of the sequence analysis software. Software packages for both the mainframe and personal computers are described.

Keywords

Alignment DNA DNA sequencing Endoplasmatisches Reticulum Internet RNA Secondary structure calculus computer database gene patterns protein protein sequence translation

Editors and affiliations

  • Annette M. Griffin
    • 1
  • Hugh G. Griffin
    • 1
  1. 1.Institute of Food ResearchNorwich Research ParkNorwichEngland

Bibliographic information

  • DOI https://doi.org/10.1385/0896032469
  • Copyright Information Humana Press 1994
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-0-89603-246-0
  • Online ISBN 978-1-59259-511-2
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • About this book