Immunotherapy of Cancer

  • Mary L. Disis
Part of the Cancer Drug Discovery and Development book series (CDD&D)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Özlem Türeci, Thorsten Klamp, Michael Koslowski, Sebastian Kreiter, Ugur Sahin
    Pages 1-19
  3. Ludmila Müller, Stephanie McArdle, Evelyna Derhovanessian, Thomas Flad, Ashley Knights, Robert Rees et al.
    Pages 21-44
  4. Heesun Kwak, Howard L. Kaufman
    Pages 87-114
  5. Weiping Zou, Tyler J. Curiel
    Pages 115-126
  6. Noweeda Mirza, Dmitry Gabrilovich
    Pages 127-138
  7. Malaya Bhattacharya-Chatterjee, Nitin Rohatgi, Sunil K. Chatterjee, Asim Saha, Rakesh Shukla, Kenneth A. Foon
    Pages 139-149
  8. Helga Bernhard, Julia Neudorfer, Kerstin Gebhard, Heinke Conrad, Dirk H. Busch, Christian Peschel
    Pages 167-179
  9. Peter A. Cohen, Mohamed Awad, Suyu Shu
    Pages 181-212
  10. Jeffrey J. Roszkowski, Michael I. Nishimura
    Pages 213-233
  11. Nancy M. Hardy, Michael R. Bishop
    Pages 235-261
  12. Michael Campoli, Soldano Ferrone
    Pages 263-284
  13. George Coukos, Jose-Ramon Conejo-Garcia
    Pages 285-301
  14. Gabriella Marincola, Francesco M. Marincola
    Pages 317-329
  15. Leisha A. Emens, R. Todd Reilly, Elizabeth M. Jaffee
    Pages 331-353

About this book

Introduction

Major scientific advances in molecular and clinical immunology have produced tremendous growth in our understanding of how cancer is recognized by the immune system, as well as in our ability to control and modulate that recognition. In Immunotherapy of Cancer, expert bench and clinical scientists join forces to concurrently review both the state of the art in tumor immunology and its clinical translation into promising practical treatments. The authors explain in each chapter the scientific basis behind such therapeutic agents as monoclonal antibodies, cytokines, vaccines, and T-cells, and illustrate their clinical manipulation to combat cancer. Additional chapters address statistical analysis-both of clinical trials and assay evaluations-methods for the discovery of antigens, adoptive T-cell therapy, and adaptive and innate immunity. The challenges in clinical trial design, the need for biomarkers of response-such as novel imaging techniques and immunological monitoring-and the new advances and directions in cancer immunotherapy are also fully examined.
Comprehensive and cutting-edge, Immunotherapy of Cancer offers immunologists an exhaustive and authoritative survey of cancer immunotherapy, as well as providing a springboard for applying the most important findings in tumor immunology to any basic laboratory program or clinical oncology practice.

Keywords

Antigen T cell cell cell therapy clinical trial cytokine cytokines imaging imaging techniques immunotherapy innate immunity interferon lymphoma tumor vaccine

Editors and affiliations

  • Mary L. Disis
    • 1
  1. 1.University of Washington School of MedicineSeattle

Bibliographic information

  • DOI https://doi.org/10.1385/1597450111
  • Copyright Information Humana Press Inc. 2006
  • Publisher Name Humana Press
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-1-58829-564-4
  • Online ISBN 978-1-59745-011-9
  • About this book