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Interferon Methods and Protocols

  • Daniel J. J. Carr

Part of the Methods in Molecular Medicine™ book series (MIMM, volume 116)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Katie R. Pang, Jashin J. Wu, David B. Huang, Stephen K. Tyring, Samuel Baron
    Pages 1-23
  3. Myriam S. Kunzi, Paula M. Pitha
    Pages 25-35
  4. Marcus J. Korth, John C. Kash, Jeffrey C. Furlong, Michael G. Katze
    Pages 37-55
  5. Jyothi Kumaran, Eleanor N. Fish
    Pages 57-67
  6. Renqiu Hu, Ke-jian Lei, Joseph Bekisz, Kathryn C. Zoon
    Pages 69-80
  7. Saumendra N. Sarkar, Mitali Pandey, Ganes C. Sen
    Pages 81-101
  8. Chandar S. Thakur, Zan Xu, Zhengfu Wang, Zachary Novince, Robert H. Silverman
    Pages 103-113
  9. Antonella Sassano, Amit Verma, Leonidas C. Platanias
    Pages 135-150
  10. W. Robert Fleischmann Jr., Tzu G. Wu
    Pages 151-166
  11. Stefano M. Santini, Caterina Lapenta, Filippo Belardelli
    Pages 167-181
  12. Stacey L. Olshalsky, Patricia Fitzgerald-Bocarsly
    Pages 183-194
  13. Cassandra M. James, Emmalene J. Bartlett, Josephine P. Mansfield, Vanessa S. Cull
    Pages 207-219
  14. Benitta John-Philip, Daniel J. J. Carr
    Pages 221-232
  15. Back Matter
    Pages 233-236

About this book

Introduction

Although some interferons (IFNs) are widely used for their antiviral, antiproliferative, and immunoregulatory properties, there are many IFN-stimulatory genes that have unknown functions, but hold great promise in medicine and biomedical research. In Interferon Methods and Protocols, leading experts actively engaged in interferon research describe in detail their optimized methods to measure type I interferon efficacy as an antiproliferative or an antiviral agent. These cutting-edge techniques range from the simple to the highly complex and serve to illuminate the signaling cascades and the activation of enzymatic pathways prompted by interferon. Two chapters add an historical perspective to the field in general, discussing the successes and failures of past and present day technology, as well as the appropriate directions for consideration of future investigations. The protocols follow the successful Methods in Molecular Medicine™ series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.
State-of-the-art and highly practical, Interferon Methods and Protocols offers researchers powerful tools not only to ascertain the functions of IFN-stimulatory gene products, but also to identify additional molecular pathways that will clarify our understanding of the many biological events influenced by IFNs.

Keywords

cancer gene therapy infection interferon research resistance vaccine virus

Editors and affiliations

  • Daniel J. J. Carr
    • 1
  1. 1.Department of OphthalmologyThe University of Oklahoma Health and Sciences CenterOklahoma City

Bibliographic information

  • DOI https://doi.org/10.1385/1592599397
  • Copyright Information Humana Press 2005
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-58829-418-0
  • Online ISBN 978-1-59259-939-4
  • Series Print ISSN 1543-1894
  • Series Online ISSN 1940-6037
  • Buy this book on publisher's site