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Molecular Diagnostics

For the Clinical Laboratorian

  • William B. Coleman
  • Gregory J. Tsongalis

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Introduction

    1. Front Matter
      Pages 1-1
  3. Basic Molecular Biology

    1. Front Matter
      Pages 11-11
    2. Paul N. Bogner, Anthony A. Killeen
      Pages 25-30
    3. Terry Amiss, Sharon Collins Presnell
      Pages 31-46
    4. William B. Coleman, Gregory J. Tsongalis
      Pages 47-55
    5. Sharon L. Ricketts
      Pages 57-61
  4. Molecular Diagnostic Technologies

    1. Front Matter
      Pages 63-63
    2. Ian M. Frayling, Emma Monk, Rachel Butler
      Pages 65-74
    3. Deborah A. Payne, Laurie E. Sower
      Pages 75-84
    4. Ulrich Broeckel, Martin J. Hessner
      Pages 111-120
    5. David Neil Hayes, Matthew Meyerson
      Pages 121-148
    6. Alexander Dobrovic
      Pages 149-160
  5. Other Clinical Diagnostic Technologies

    1. Front Matter
      Pages 161-161
    2. Joseph A. DiGiuseppe
      Pages 163-172
    3. Martha B. Keagle
      Pages 173-187
    4. Suneel D. Mundle, Robert J. Koska
      Pages 189-202
    5. John Hunt, Larissa Davydova, Richard W. Cartun, Maria Baiulescu
      Pages 203-217
    6. C. Robert Bagnell Jr
      Pages 219-224
  6. Quality Assurance in the Molecular Diagnostics Laboratory

    1. Front Matter
      Pages 225-225
    2. Marlene Sabbath-Solitare, Selwyn J. Baptist, Teresita Cuyegkeng Redondo
      Pages 227-236
    3. Brent L. Seaton
      Pages 237-241
    4. John P. Jakupciak, Catherine D. O’Connell
      Pages 243-246
    5. Andrea Ferreira-Gonzalez, Carleton T. Garrett
      Pages 247-256
  7. Applications Of Molecular Diagnostics for Genetic Diseases

    1. Front Matter
      Pages 257-257
    2. Elaine Weidenhammer, Gregory J. Tsongalis
      Pages 259-266
    3. Narasimhan Nagan, Christopher J. Klein, D. Brian Dawson, Myra J. Wick, Stephen N. Thibodeau
      Pages 267-280
    4. Amy Potter, John A. Phillips III
      Pages 281-294
    5. Enrique Ballesteros
      Pages 311-320
    6. Eugene H. Lewis III, Myra J. Lewis, Jean A. Amos, Gregory J. Tsongalis
      Pages 321-327
    7. Karen McCullough
      Pages 341-346
  8. Applications of Molecular Diagnostics for Human Cancers

    1. Front Matter
      Pages 347-347
    2. William B. Coleman, Gregory J. Tsongalis
      Pages 349-374
    3. Ian M. Frayling, Lisa Happerfield, Christopher Mattocks, Kim Oakhill, Mark J. Arends
      Pages 375-392
    4. William N. Rezuke Jr, Gregory J. Tsongalis
      Pages 393-413
    5. Pei Lin, L. Jeffrey Medeiros
      Pages 415-436
  9. Applications of Molecular Diagnosis for Infectious Diseases

    1. Front Matter
      Pages N1-N1
    2. Theresa M. Voytek, Gregory J. Tsongalis
      Pages 447-451
    3. Angela M. Caliendo, Charles E. Hill
      Pages 453-459
    4. D. Robert Dufour
      Pages 461-471
    5. Angela M. Caliendo, Nell S. Lurain
      Pages 473-482
  10. Applications of Molecular Diagnostics To Identity-Based Testing

    1. Front Matter
      Pages 483-483
    2. John L. Schmitz
      Pages 485-493

About this book

Introduction

Taking advantage of the many major advances that have occurred since their groundbreaking first edition was published, William B. Coleman and Gregory J. Tsongalis have updated and expanded their highly praised tutorial guide to molecular diagnostic techniques to include not only improved traditional methods, but also totally new molecular technologies, some not yet in routine use. The authors offer cutting-edge molecular diagnostics for genetic disease, human cancers, infectious diseases, and identity testing, as well as new insights into the question of quality assurance in the molecular diagnostics laboratory. Additional chapters address other technologies found in the clinical laboratory that are complementary to molecular diagnostic methodologies, and also discuss genetic counseling and the ethical and social issues involved with nucleic acid testing.

Authoritative and state-of-the-art, Molecular Diagnostics: For the Clinical Laboratorian, 2nd Edition is the essential textbook of choice for anyone working in molecular diagnostics and who wants to remain current with this rapidly changing field.

Keywords

DNA DNA sequencing Laboratory PCR bioinformatics diagnostics gene expression genes genetics hybridization infectious diseases polymer virus

Editors and affiliations

  • William B. Coleman
    • 1
  • Gregory J. Tsongalis
    • 2
  1. 1.Department of Pathology and Laboratory MedicineUniversity of North Carolina School of MedicineChapel HillUSA
  2. 2.Department of PathologyDartmouth-Hitchcock Medical CenterLebanonUSA

Bibliographic information

  • DOI https://doi.org/10.1385/1592599281
  • Copyright Information Humana Press 2005
  • Publisher Name Humana Press
  • eBook Packages Medicine
  • Print ISBN 978-1-58829-356-5
  • Online ISBN 978-1-59259-928-8
  • Buy this book on publisher's site