The Principles of Clinical Cytogenetics

  • Steven L. Gersen
  • Martha B. Keagle

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Basic Concepts and Background

    1. Front Matter
      Pages 1-1
    2. Steven L. Gersen
      Pages 3-8
    3. Martha B. Keagle
      Pages 9-25
    4. Avirachan Tharapel
      Pages 27-57
  3. Examining and Analyzing Chromosomes

    1. Front Matter
      Pages 59-59
    2. Martha B. Keagle, Steven L. Gersen
      Pages 63-79
    3. Christopher McAleer
      Pages 81-91
    4. Michael S. Watson, Steven L. Gersen
      Pages 93-112
    5. Steven L. Gersen, Lotte Downey
      Pages 113-130
  4. Clinical Cytogenetics

    1. Front Matter
      Pages 131-131
    2. Jin-Chen C. Wang
      Pages 133-164
    3. Kathleen Kaiser-Rogers, Kathleen Rao
      Pages 165-206
    4. Cynthia M. Powell
      Pages 207-246
    5. Linda Marie Randolph
      Pages 247-265
    6. Linda Marie Randolph
      Pages 267-321
    7. Solveig M. V. Pflueger
      Pages 323-345
    8. Xiao-Xiang Zhang
      Pages 347-361
  5. Cancer Cytogenetics

    1. Front Matter
      Pages 363-363
    2. Rizwan C. Naeem
      Pages 365-420
    3. Jonathan A. Fletcher
      Pages 421-451
  6. Fluorescence In Situ Hybridization

    1. Front Matter
      Pages 453-453
    2. Daynna J. Wolff, Stuart Schwartz
      Pages 455-489
  7. Beyond Chromosomes

    1. Front Matter
      Pages 491-491
    2. Dana C. Crawford, Patricia N. Howard-Peebles
      Pages 495-513
    3. Jin-Chen C. Wang
      Pages 515-540
    4. Sarah Hutchings Clark
      Pages 541-558
  8. Back Matter
    Pages 559-596

About this book


In this thoroughly revised and expanded edition of a highly praised classic, The Principles of Clinical Cytogenetics, a panel of hands-on experts update their survey of the basic concepts and interpretations involved in chromosome analysis to include the many advances that have occurred in the field. Among the highlights are a full section devoted to advances in fluorescence in situ hybridization (FISH) technology, increased coverage of cancer cytogenetics-both hematopoietic neoplasms and tumor cytogenetics-and new chapters on chromosome instability and the cytogenetics of infertility. The book also reflects major advances in instrumentation and the transition from FAB to World Health Organization nomenclature for hematopoietic disorders.
State-of-the-art and readily accessible, The Principles of Clinical Cytogenetics, 2nd Edition offers physicians who depend on the cytogenetics laboratory for the diagnosis of their patients, students in cytogenetics programs, and cytogeneticists the clear understanding they need to carry out and interpret their test results rapidly.


Chromosom DNA FISH Fluoreszenz in situ-Hybridisierung cell division genetics hybridization microscopy

Editors and affiliations

  • Steven L. Gersen
    • 1
  • Martha B. Keagle
    • 2
  1. 1.AmeriPath Inc.USA
  2. 2.School of Allied Health ProfessionsUniversity of ConnecticutStorrs

Bibliographic information