Pain Research

Methods and Protocols

  • Z. David Luo

Part of the Methods in Molecular Medicine book series (MIMM, volume 99)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Z. David Luo
    Pages 1-10
  3. Jeffrey W. Allen, Tony L. Yaksh
    Pages 11-23
  4. Jeffrey W. Allen, Tony L. Yaksh
    Pages 25-34
  5. Jin Mo Chung, Hee Kee Kim, Kyungsoon Chung
    Pages 35-45
  6. Thies Lindenlaub, Claudia Sommer
    Pages 47-53
  7. Nigel A. Calcutt
    Pages 55-65
  8. Erin D. Milligan, Steven F. Maier, Linda R. Watkins
    Pages 67-89
  9. Emiliano S. Higuera, Z. David Luo
    Pages 91-98
  10. Martin Marsala
    Pages 99-108
  11. Shelle A. Malkmus, Tony L. Yaksh
    Pages 109-121
  12. Koichi Iwata, Yuji Masuda, Ke Ren
    Pages 123-137
  13. Louise C. Stanfa, Anthony H. Dickenson
    Pages 139-153
  14. Maria Schäfers, David Cain
    Pages 155-166
  15. Thomas H. Burkey, Cynthia M. Hingtgen, Michael R. Vasko
    Pages 189-202
  16. Virginia S. Seybold, Lia G. Abrahams
    Pages 203-213
  17. Fredrik Kamme, Jessica Zhu, Lin Luo, Jingxue Yu, Da-Thao Tran, Bernhard Meurers et al.
    Pages 215-223
  18. Hong Qing Guo, Sandra R. Chaplan
    Pages 225-238
  19. Stephen J. Walker, Travis J. Worst, Willard M. Freeman, Kent E. Vrana
    Pages 239-253
  20. Guoping Feng, Jing Lu, Jimmy Gross
    Pages 255-267
  21. Andrée Dierich, Brigitte L. Kieffer
    Pages 269-299
  22. Back Matter
    Pages 301-303

About this book


Despite significant advances in molecular biology techniques and in our understanding of the physiology and the behavioral pharmacology of pain transduction, effective, target-specific therapeutic agents for chronic pain are still lacking. In Pain Research: Methods and Protocols, leading researchers who have first-hand experience describe, in step-by-step detail, diverse and novel techniques for dissecting the molecular mechanisms of pain transduction. These readily reproducible methods employ a variety of multidisciplinary approaches ranging from animal pain models and single neutron selection to in vitro single-cell mRNA amplification. The collection includes not only standard, cutting-edge methods, but also novel techniques only recently applied to pain research. The protocols follow the successful Methods in Molecular Biology™ series format, each one offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.
Versatile and easy-to-use, Pain Research: Methods and Protocols offers today's pain researchers in academic and pharmaceutical laboratories powerful tools to unravel the cellular and molecular complexity of pain transduction and set the stage for the next generation of pain medications.

Editors and affiliations

  • Z. David Luo
    • 1
  1. 1.Department of AnesthesiologyUniversity of California Irvine Medical CenterIrvine

Bibliographic information

  • DOI
  • Copyright Information Humana Press 2004
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-58829-103-5
  • Online ISBN 978-1-59259-770-3
  • Series Print ISSN 1543-1894
  • Series Online ISSN 1940-6037
  • Buy this book on publisher's site