DNA Vaccines

Methods and Protocols

  • Douglas B. Lowrie
  • Robert G. Whalen

Part of the Methods in Molecular Medicine™ book series (MIMM, volume 29)

Table of contents

  1. Front Matter
    Pages i-xix
  2. Anthony P. Green
    Pages 1-9
  3. Joachim Schorr, Peter Moritz, Martin Schleef
    Pages 11-21
  4. Nancy L. Shen, Jukka Hartikka, Nancy A. Horn, Marston Manthorpe, Magda Marquet
    Pages 23-34
  5. Derek Gregory, Ricardo E. Tascon, Douglas B. Lowrie
    Pages 35-36
  6. Thomas Tüting, Jonathan Austyn, Walter J. Storkus, Louis D. Falo Jr.
    Pages 37-64
  7. Sylvia van Drunen Littel-van den Hurk, Ralph P. Braun, Lorne A. Babiuk
    Pages 79-94
  8. Cynthia L. Brazolot Millan, Heather L. Davis
    Pages 95-98
  9. Joël Heppell, Heather L. Davis
    Pages 99-103
  10. Eric D. Anderson, Jo-Ann C. Leong
    Pages 105-121
  11. Antonio Rosato, Gabriella Milan, Annalisa Zambon, Paola Zanovello, Dino Collavo
    Pages 123-132
  12. John H. Van Uden, Eyal Raz
    Pages 145-168
  13. Risini Weeratna, Arthur M. Krieg, Heather L. Davis
    Pages 169-172
  14. Charles F. Reich, David S. Pisetsky
    Pages 173-184
  15. Jon Norman, Jukka Hartikka, Pamela Strauch, Marston Manthorpe
    Pages 185-196
  16. Kenji Okuda, Susumu Kawamoto, Jun Fukushima
    Pages 197-204
  17. Jong J. Kim, David B. Weiner
    Pages 205-220
  18. Holden T. Maecker, Athanasia Syrengelas, Ronald Levy
    Pages 221-239
  19. Hildegund C. J. Ertl, Susanna Pasquini, Zhenning He, Hongying Deng, Louise Showe, Wynetta Giles-Davis et al.
    Pages 251-260
  20. Donald L. Lodmell, Nancy B. Ray, Larry C. Ewalt
    Pages 261-266
  21. Russell J. Mumper, Harry C. Ledebur Jr., Alain P. Rolland, Eric Tomlinson
    Pages 267-286
  22. Michael J. McCluskie, Heather L. Davis
    Pages 287-295
  23. Michael D. Macklin, Robert J. Drape, William F. Swain
    Pages 297-303
  24. Gregory Gregoriadis, Brenda McCormack, Mia Obrenovich, Yvonne Perrie
    Pages 305-311
  25. Reinhold Schirmbeck, Jan von Kampen, Karin Metzger, Jens Wild, Beate Grüner, Martin Schleef et al.
    Pages 313-322
  26. Franck G. Sturtz, Yunsheng Li, Janine Shulok, H. Ralph Snodgrass, Xiao-zhuo Chen
    Pages 323-333
  27. Jochen Heinrich, Bettina Strack, Michael Nawrath, Jovan Pavlovic, Karin Moelling
    Pages 335-344
  28. I. Frank Ciernik, David P. Carbone
    Pages 345-353
  29. Shan Lu, Steve Manning, James Arthos
    Pages 355-374
  30. Alexis P. Godillot, Qiong Fang, Terry Higgins, Catherine Pachuk, Jean Boyer, David B. Weiner et al.
    Pages 375-395
  31. Ari Waisman
    Pages 397-403
  32. Delin Zhu, Myfanwy B. Spellerberg, Catherine A. King, Jason Rice, Andrew R. Thompsett, Freda K. Stevenson
    Pages 405-423
  33. Waltraud Böhm, Martin Schleef, Stefan Thoma, Reinhold Schirmbeck, Jörg Reimann
    Pages 425-437
  34. Fu-chun Zhang, Ni Wang, Dong-mei Liu, Youli Jian, You-zhen Chen, Xiao-zhou Shen et al.
    Pages 439-449
  35. Mark Roman, Helen Tighe, Hans L. Spiegelberg, David Broide, Eyal Raz
    Pages 451-472
  36. Richard B. Ciccarelli, Catherine J. Pachuk, Manoj Samuel, Laurie A. Winter, C. Satishchandran
    Pages 473-488
  37. Gil Mor, Mariel Eliza
    Pages 489-497
  38. James S. Robertson, Elwyn Griffiths
    Pages 499-508
  39. Back Matter
    Pages 509-529

About this book


In DNA Vaccines: Methods and Protocols, state-of-the-art review articles by leading experts summarize how to develop and employ the highly promising new DNA vaccines, what clinical results can be expected from their use, and what is known about how they work. Key topics range from vaccine design and construction to preparation and delivery methods, including the use of classical adjuvants, "genetic adjuvants," and the immunostimulatory properties of DNA and selected oligonucleotide sequences. Several contributors provide strategic ideas on antigen engineering and describe the particularly novel applications of DNA vaccine methodology that have recently emerged. In addition, there is a discussion of dendritic cells and antigen-presenting cells, the understanding of whose actions holds great promise for modulating the immune response, and thus for treating disease. Cutting-edge and comprehensive, DNA Vaccines: Methods and Protocols provides a broad panorama of the methods and thinking from which the vaccines of tomorrow will evolve, and so constitutes an invaluable sourcebook for both experts developing new applications and newcomers who want to gain mastery of the techniques and problems involved.

Editors and affiliations

  • Douglas B. Lowrie
    • 1
  • Robert G. Whalen
    • 2
  1. 1.Mycobacterial Research LaboratoryLondonUK
  2. 2.Maxygen Inc.Redwood City

Bibliographic information

  • DOI
  • Copyright Information Humana Press 2000
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-0-89603-580-5
  • Online ISBN 978-1-59259-688-1
  • Series Print ISSN 1543-1894
  • Series Online ISSN 1940-6037
  • Buy this book on publisher's site