Hepatitis B and D Protocols

Volume 2: Immunology, Model Systems, and Clinical Studies

  • Robert K. Hamatake
  • Johnson Y. N. Lau

Part of the Methods in Molecular Medicine™ book series (MIMM, volume 96)

Table of contents

  1. Front Matter
    Pages i-xxiii
  2. Viral-Specific Immunological and Other Host Responses

    1. Front Matter
      Pages 1-1
    2. Darren S. Miller, Edward M. Bertram, Catherine A. Scougall, Ieva Kotlarski, Allison R. Jilbert
      Pages 3-25
    3. Stephan Menne, Paul J. Cote
      Pages 27-36
    4. Michael Geissler, Robert Weth, Christian F. Grimm, Dörte Ortmann, Hubert E. Blum
      Pages 43-54
    5. Michelina Nascimbeni, Barbara Rehermann
      Pages 65-83
    6. Shilpa Chokshi, Nikolai V. Naoumov
      Pages 97-109
    7. Ren-Shiang Lee, Shih-Jer Hsu, Li-Rung Huang, Hui-Lin Wu, Shiou-Lin Lin, Ding-Shinn Chen et al.
      Pages 111-128
  3. In Vitro and In Vivo Models

    1. Front Matter
      Pages 129-129
    2. Fritz von Weizsäcker, Josef Köck, Sabine MacNelly, Shaotang Ren, Hubert E. Blum, Michael Nassal
      Pages 153-161
    3. Norma D. Churchill, Tomasz I. Michalak
      Pages 175-187
    4. Olivier Hantz, Fabien Zoulim
      Pages 189-197
    5. Martin Sprinzl, Jérôme Dumortier, Ulrike Protzer
      Pages 209-218
    6. Harriet C. Isom, Ayman M. Abdelhamed, John P. Bilello, Thomas G. Miller
      Pages 219-237
    7. Jörg Petersen, Martin R. Burda, Maura Dandri, Charles E. Rogler
      Pages 253-260
    8. Lucyna Cova, Fabien Zoulim
      Pages 261-268
    9. Mark A. Feitelson, Jonathan D. Larkin, Raymond F. Schinazi
      Pages 269-287
    10. Pascal Gagneux, Elaine A. Muchmore
      Pages 289-318
    11. Jinhong Chang, Anthony Lerro, John M. Taylor
      Pages 343-349
    12. Thomas B. Macnaughton, Michael M. C. Lai
      Pages 351-357
  4. Antiviral Testing and Clinical Studies

    1. Front Matter
      Pages 359-359
    2. Eric J. Bourne, Josée Gauthier, Vincent A. Lopez, Lynn D. Condreay
      Pages 379-386
    3. Michael P. Manns, Johannes Hadem, Heiner Wedemeyer
      Pages 415-443
    4. Bruno B. Bordier, Jeffrey S. Glenn
      Pages 539-553
  5. Back Matter
    Pages 555-572

About this book


Despite the availability of an effective vaccine, there are still 400 million people worldwide who are chronically infected with the hepatitis B and D viruses (HBV and HDV), and more work still needs to be done in all of the key areas of managing the disease. In Hepatitis B and D Protocols, leading investigators and clinicians have joined forces to create a broad-ranging collection of cutting-edge techniques for the study of HBV and HDV infections and for the development of therapies to treat them. In this second of two volumes, Immunology, Model Systems, and Clinical Studies, the authors focus on protocols for the study of host immune responses to infection, in vitro and in vivo models of infection, and the development of antivirals. Each fully tested protocol is described in step-by-step detail by an established expert in the field and includes a background introduction outlining the principle underlying the technique, equipment and reagent lists, and tips on troubleshooting and avoiding known pitfalls. An accompanying first volume, Detection, Genotypes, and Characterization, contains user-friendly protocols for the identification and quantification of viral markers, the detection and impact of viral variants, and the study of the viral life cycle.
Taken together, Hepatitis B and D Protocols, Volume 1: Detection, Genotypes, and Characterization and Volume 2: Immunology, Model Systems, and Clinical Studies offer both new and experienced investigators an encyclopedic collection of powerful tools for studying HBV and HDV infections, as well as an essential resource for finding new therapies to treat chronically infected patients.

Editors and affiliations

  • Robert K. Hamatake
    • 1
  • Johnson Y. N. Lau
    • 1
  1. 1.Ribapharm Inc.Costa Mesa

Bibliographic information

  • DOI
  • Copyright Information Humana Press 2004
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-58829-108-0
  • Online ISBN 978-1-59259-670-6
  • Series Print ISSN 1543-1894
  • Series Online ISSN 1940-6037
  • Buy this book on publisher's site