Hepatitis B and D Protocols

Volume 1: Detection, Genotypes, and Characterization

  • Robert K. Hamatake
  • Johnson Y. N. Lau

Part of the Methods in Molecular Medicine book series (MIMM, volume 95)

Table of contents

  1. Front Matter
    Pages i-xxiv
  2. Detection of Viral Markers

    1. Front Matter
      Pages 1-1
    2. Stefan Zeuzemro
      Pages 3-13
    3. Wei Zhang, Hans Jörg Hacker, Maria Mildenberger, Qin Su, Claus H. Schröder
      Pages 29-40
    4. Scott Bowden, Kathy Jackson, Margaret Littlejohn, Stephen Locarnini
      Pages 41-50
    5. Jane W. S. Fang, Johnson Y. N. Lau
      Pages 65-69
    6. Antonina Smedile, Maria Grazia Niro, Mario Rizzetto
      Pages 85-93
    7. Thomas B. Macnaughton, Michael M. C. Lai
      Pages 99-105
    8. Karim Abid, Francesco Negro
      Pages 107-111
  3. Viral Genotypes and Variants

    1. Front Matter
      Pages 113-113
    2. Ashraf A. Basuni, William F. Carman
      Pages 115-124
    3. Anna Ayres, Stephen Locarnini, Angeline Bartholomeusz
      Pages 125-149
    4. Sija De Gendt, Fred Shapiro, Jelena Juras, Els Van Assche, Geert Maertens, Erwin Sablon
      Pages 175-186
  4. Molecular Biological Characterization

    1. Front Matter
      Pages 187-187
    2. Jie Li, Yanyan Zheng, Jinah Choi, Jing-hsiung Ou
      Pages 227-233
    3. Anneke K. Raney
      Pages 303-314
    4. Charles E. Rogler
      Pages 327-337
  5. Back Matter
    Pages 339-349

About this book


Despite the availability of an effective vaccine, there are still 400 million people worldwide who are chronically infected with the hepatitis B and D viruses (HBV and HDV), and more work still needs to be done in all of the key areas of managing the disease. In Hepatitis B and D Protocols, leading investigators and clinicians have joined forces to create a broad-ranging collection of core techniques for the study of HBV and HDV infections and for the development of therapies to treat them. In this first of two volumes Detection, Genotypes, and Characterization, the authors focus on readily reproducible molecular methods for the identification and quantification of viral markers, the detection and impact of viral variants, and the study of the viral life cycle. Each fully tested protocol is described in step-by-step detail by an established expert in the field and includes a background introduction outlining the principle underlying the technique, equipment and reagent lists, and tips on troubleshooting and avoiding known pitfalls. An accompanying second volume, Immunology, Model Systems, and Clinical Studies, contains user-friendly protocols for the study of host immune responses to infection, in vitro and in vivo models of infection, and the development of antivirals.
Taken together, Hepatitis B and D Protocols, Volume 1: Detection, Genotypes, and Characterization and Volume 2: Immunology, Model Systems, and Clinical Studies offer both new and experienced investigators an encyclopedic collection of powerful tools for studying HBV and HDV infections, as well as an essential resource for finding new therapies to treat chronically infected patients.


Hepatitis antigen infection infections interferon vaccine virus

Editors and affiliations

  • Robert K. Hamatake
    • 1
  • Johnson Y. N. Lau
    • 1
  1. 1.Ribapharm Inc.Costa Mesa

Bibliographic information

  • DOI
  • Copyright Information Humana Press 2004
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-58829-105-9
  • Online ISBN 978-1-59259-669-0
  • Series Print ISSN 1543-1894
  • Series Online ISSN 1940-6037
  • Buy this book on publisher's site