Chiral Separations

Methods and Protocols

  • Gerald Gübitz
  • Martin G. Schmid

Part of the Methods in Molecular Biology book series (MIMB, volume 243)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Gerald Gübitz, Martin G. Schmid
    Pages 1-28
  3. Kurt Günther, Peter Richter, Klaus Möller
    Pages 29-59
  4. Clifford R. Mitchell, Daniel W. Armstrong
    Pages 61-112
  5. Peter Spégel, Lars I. Andersson, Staffan Nilsson
    Pages 217-229
  6. Leo Hsu, Genevieve Kennedy, Gerald Terfloth
    Pages 247-253
  7. Wioleta Maruszak, Martin G. Schmid, Gerald Gübitz, Elzbieta Ekiert, Marek Trojanowicz
    Pages 275-289
  8. Gunnar Johansson, Roland Isaksson, Göran Pettersson
    Pages 307-315
  9. Martin G. Schmid, Gerald Gübitz
    Pages 317-321
  10. Koji Otsuka, Shigeru Terabe
    Pages 355-363
  11. Marja-Liisa Riekkola, Heli Sirén
    Pages 365-374
  12. Dorothee Wistuba, Jingwu Kang, Volker Schurig
    Pages 401-409
  13. Peter Spégel, Jakob Nilsson, Staffan Nilsson
    Pages 411-424
  14. Back Matter
    Pages 425-432

About this book


Methods for enantiomer separation are very important for controlling synthesis, for checking racemization, for enantiomeric purity control, and for pharmacokinetic studies. In Chiral Separations: Methods and Protocols, prominent experts from around the world detail the chromatographic and electroseparation techniques they have developed for chiral separations on an analytical scale. Described in step-by-step detail to ensure successful experimental results, the procedures are presented as either general methods or as specific applications to substance classes and special compounds, with emphasis on high performance liquid chromatography and capillary electrophoresis techniques, but also including thin layer chromotogrphic, gas chromatographic, and supercritical fluid chromatographic as well as recent electrochromotographic techniques. Each fully tested protocol includes an introduction to the principle underlying the method, equipment and reagent lists, and helpful notes on troubleshooting and avoiding known pitfalls.
Up-to-date and highly practical, Chiral Separations: Methods and Protocols will help both novice and advanced users not only choose optimal methods for their separation problems, but also readily obtain successful results.

Editors and affiliations

  • Gerald Gübitz
    • 1
  • Martin G. Schmid
    • 1
  1. 1.Institute of Pharmaceutical Chemistry and Pharmaceutical TechnologyKarl-Franzens UniversityGrazAustria

Bibliographic information

  • DOI
  • Copyright Information Humana Press 2004
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-58829-150-9
  • Online ISBN 978-1-59259-648-5
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site