Diabetes Mellitus

Methods and Protocols

  • Sabire Özcan

Part of the Methods in Molecular Biology™ book series (MIMM, volume 83)

Table of contents

  1. Front Matter
    Pages i-x
  2. Insulin Production

    1. Front Matter
      Pages 1-1
    2. Colleen B. Kelly, Libby A. Blair, John A. Corbett, Anna L. Scarim
      Pages 3-14
    3. Geert Stangé, Mark Van De Casteele, Harry Heimberg
      Pages 15-22
    4. Marcela Brissova, Wendell E. Nicholson, Masakazu Shiota, Alvin C. Powers
      Pages 23-45
    5. Susan C. Campbell, Wendy M. Macfarlane
      Pages 47-49
    6. Susan C. Campbell, Wendy M. Macfarlane
      Pages 51-59
    7. Marcelina Párrizas, Sylvia F. Boj, Reini F. Luco, Miguel Angel Maestro, Jorge Ferrer
      Pages 61-71
    8. Amber L. Mosley, Sabire Özcan
      Pages 73-79
    9. Dennis G. Karounos, Susan E. Goes
      Pages 81-90
  3. Insulin Action

    1. Front Matter
      Pages 91-91
    2. Shuichi Okada, Masatomo Mori, Jeffrey E. Pessin
      Pages 93-96
    3. Jaganathan Lakshmanan, Jeffrey S. Elmendorf, Sabire özcan
      Pages 97-103
    4. Li-Ping Wang, Scott A. Summers
      Pages 127-136
    5. Kyle L. Hoehn, Scott A. Summers
      Pages 137-144
    6. Maggie M-Y. Chi, Kelle H. Moley
      Pages 171-178
  4. Back Matter
    Pages 187-192

About this book


About 17 million Americans suffer from diabetes mellitus, a disease caused by defects in insulin production, insulin action, or both, and also a leading cause of kidney failure, blindness, and amputations. In Diabetes Mellitus: Methods and Protocols, leading researchers and clinical investigators describe their cutting-edge techniques for studying these defects at both the molecular and biochemical levels. Written in step-by-step detail to ensure ready reproducibility and robust results, these techniques allow investigators, both novices and those already active in the field, to study every major facet of insulin production and action. Each protocol includes an introduction to the technique, an explanation of its application, and a list of materials. Practical notes discuss how to avoid pitfalls, as well as how to adapt the methods to your own research.
Cutting-edge and highly practical, Diabetes Mellitus: Methods and Protocols provides basic scientists and clinical researchers, both experienced investigators and those new to the field, all the critical tools needed for the productive study of diabetes mellitus today.

Editors and affiliations

  • Sabire Özcan
    • 1
  1. 1.Department of Molecular and Cellular BiochemistryUniversity of Kentucky Medical CollegeLexington

Bibliographic information

  • DOI
  • Copyright Information Humana Press 2003
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-58829-148-6
  • Online ISBN 978-1-59259-377-4
  • Series Print ISSN 1543-1894
  • Series Online ISSN 1940-6037
  • Buy this book on publisher's site