Protein Structure Prediction

Methods and Protocols

  • David M. Webster

Part of the Methods in Molecular Biology™ book series (MIMB, volume 143)

Table of contents

  1. Front Matter
    Pages i-x
  2. Desmond G. Higgens, William R. Taylor
    Pages 1-18
  3. William R. Taylor
    Pages 19-32
  4. Chris P. Ponting, Ewan Birney
    Pages 53-69
  5. Burkhard Rost, Chris Sander
    Pages 71-95
  6. Boris A. Reva, Alexei V. Finkelstein, Jeffrey Skolnick
    Pages 155-174
  7. Steffen Schulze-Kremer
    Pages 175-222
  8. Enoch S. Huang, Ram Samudrala, Britt H. Park
    Pages 223-245
  9. Marc De Maeyer, Johan Desmet, Ignace Lasters
    Pages 265-304
  10. Robert B. Russell
    Pages 305-324
  11. Mark S. P. Sansom, Leo Davison
    Pages 325-347
  12. D. Eric Walters
    Pages 349-358
  13. Johan Desmet, Marc De Maeyer, Jan Spriet, Ignace Lasters
    Pages 359-376
  14. Haim J. Wolfson, Ruth Nussinov
    Pages 377-397
  15. Michael J. E. Sternberg, Henry A. Gabb, Richard M. Jackson, Gidon Moont
    Pages 399-415
  16. Back Matter
    Pages 417-422

About this book


The deeper understanding of protein structure now emerging from cutting-edge research is not only illuminating evolutionary and biochemical mechanisms, but also promises enormous ramifications for molecular medicine, as well as for biotechnology, biophysics, biology, genetics, and other molecular sciences. In Protein Structure Prediction: Methods and Protocols, world-class investigators detail their most successful methods-and the theory behind them-for delineating the shape, form, and function of proteins. The protocols range from basic to advanced and include sequence alignment, the prediction of transmembrane protein structure, and the development of suitable folding potentials. There are also techniques for receptor site prediction, the identification of motifs and domains, the comparative modeling of proteins, the docking of peptides and ligands, and ab initio approaches to protein loop and side-chain prediction. To ensure robust and successful experimental results, each protocol contains step-by-step instructions, as well as tips on pitfalls to avoid and how procedures may be optimized for different systems.
Comprehensive, accessible, and highly practical, Protein Structure Prediction: Methods and Protocols offers protein researchers, structural biologists, and other investigators a critical synthesis of the latest research results, as well as the vital guidance needed to understand the structure and interaction of proteins and peptides.

Editors and affiliations

  • David M. Webster
    • 1
  1. 1.Southern Cross MolecularBathUK

Bibliographic information

  • DOI
  • Copyright Information Humana Press 2000
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-0-89603-637-6
  • Online ISBN 978-1-59259-368-2
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site