Lung Cancer

Volume 1: Molecular Pathology Methods and Reviews

  • Barbara Driscoll

Part of the Methods in Molecular Medicine™ book series (MIMM, volume 74)

Table of contents

  1. Front Matter
    Pages i-xxi
  2. Introduction

    1. Ignacio I. Wistuba, Adi F. Gazdar
      Pages 3-28
  3. Etiology and Classification of Lung Tumors

    1. Kirsi Vähäkangas
      Pages 43-59
    2. Judy M. Coulson, Marta Ocejo-Garcia, Penella J. Woll
      Pages 61-73
    3. Kushagra Katariya, Richard J. Thurer
      Pages 75-86
  4. Molecular Abnormalities in Lung Cancer

    1. Gautam Maulik, Takashi Kijima, Ravi Salgia
      Pages 113-125
    2. Alfredo MartÍnez, Teresa A. Lehman, Rama Modali, James L. Mulshine
      Pages 187-200
    3. Kristiina Järvinen, Ylermi Soini, Vuokko L. Kinnula
      Pages 211-222
    4. Armando E. Fraire, Bruce A. Woda, Louis Savas, Zhong Jiang
      Pages 243-249
    5. Eva Szabo
      Pages 251-258
    6. Yoshihiro Nambu, David G. Beer
      Pages 259-266
    7. Lori D. Dwyer-Nield, David Dinsdale, J. John Cohen, Margaret K. T. Squier, Alvin M. Malkinson
      Pages 283-297
    8. Patrick P. Koty, Haifan Zhang, Wendong Lei, Mark L. Levitt
      Pages 309-326
    9. Amir Onn, Roy S. Herbst
      Pages 329-348
    10. Melissa Lim, David M. Jablons
      Pages 349-356
    11. Kenneth J. O’Byrne, Jonathan Goddard, Alexandra Giatromanolaki, Michael I. Koukourakis
      Pages 357-373
    12. Marsha A. Moses, Michael S. O’Reilly
      Pages 375-390
    13. Keiko Hiyama, Eiso Hiyama
      Pages 401-412
    14. Nandan Bhattacharyya, Sipra Banerjee
      Pages 413-438
  5. Lung Cancer Model Systems

    1. Robert M. Hoffman
      Pages 457-464
    2. Kam-Meng Tchou-Wong, William N. Rom
      Pages 465-480
    3. Lloyd A. Culp, Wen-Chang Lin, Nanette Kleinman, Julianne L. Holleran, Carson J. Miller
      Pages 507-524
    4. Bruce C. Baguley, Elaine S. Marshall, Timothy I. Christmas
      Pages 527-544
    5. Leslie-Ann M. Hall, Candice M. Krauthauser, Roseanne S. Wexler, Andrew M. Slee, Janet S. Kerr
      Pages 545-566
  6. Back Matter
    Pages 567-594

About this book


Molecular-based laboratory methods can help significantly in the diagnosis and treatment of lung cancer, a leading cause of death worldwide. In Lung Cancer, Volume 1: Molecular Pathology Methods and Reviews, leading physicians, scientists, and noted researchers review novel methods for determining the etiology of a variety of lung cancers and present readily reproducible techniques for examining the associated multitude of genetic abnormalities. The methods described make it possible to detect these alterations at the cellular, DNA, and protein levels, to study the development of lung cancer in vitro and in vivo-either in situ or in the form of metastases-and to test targeted therapies with detailed model systems. An animal models section gives explicit instructions for setting up and testing these systems, which are rarely described in the literature. A companion volume, Lung Cancer, Volume 2: Diagnostic and Therapeutic Methods and Reviews, concentrates on diagnosing lung cancer through molecular analysis of clinical samples and providing a variety of novel therapies.
Comprehensive and informative, Lung Cancer, Volume 1: Molecular Pathology Methods and Reviews illuminates the etiology of lung cancer and provides reliable techniques for detecting the responsible genetic mutations at the cellular, DNA, and protein levels. Together, the two volumes constitute an unprecedented resource for those who wish to better understand how this disease is being diagnosed and treated and what novel techniques may be available to improve both processes.

Editors and affiliations

  • Barbara Driscoll
    • 1
  1. 1.Children’s HospitalLos AngelesUSA

Bibliographic information

  • DOI
  • Copyright Information Humana Press 2003
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Protocols
  • Print ISBN 978-0-89603-985-8
  • Online ISBN 978-1-59259-323-1
  • Series Print ISSN 1543-1894
  • Series Online ISSN 1940-6037
  • Buy this book on publisher's site