Hemostasis and Thrombosis Protocols

  • David J. Perry
  • K. J. Pasi

Part of the Methods in Molecular Medicine™ book series (MIMM, volume 31)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Introduction

    1. Front Matter
      Pages 1-1
    2. K. John Pasi
      Pages 3-21
  3. Basic Techniques

    1. Front Matter
      Pages 23-23
    2. David J. Perry
      Pages 25-30
    3. David J. Perry
      Pages 31-38
    4. David J. Perry
      Pages 39-48
    5. Helen L. Devereux
      Pages 55-61
    6. David J. Perry, Flora Peyvandi
      Pages 63-64
    7. Peter R. Winship, Jonathan R. K. Spray
      Pages 65-81
  4. Methods of Mutational Analysis

  5. Methods for Analyzing Inherited/Acquired Disorders of Hemostasis

    1. Front Matter
      Pages 131-131
    2. Naushin H. Waseem, Richard Bagnall, Peter M. Green, Francesco Giannelli
      Pages 133-149
    3. Peter M. Green
      Pages 159-167
    4. Mohammed S. Enayat, Gurcharan K. Surdhar
      Pages 179-186
    5. Mohammed S. Enayat
      Pages 187-200
    6. Karen M. Johnson, John H. McVey
      Pages 211-221
    7. David J. Perry
      Pages 223-229
    8. Roger Luddington
      Pages 239-247
    9. Núria Sala, Yolanda Espinosa-Parrilla
      Pages 249-268
    10. Karen P. Brown
      Pages 275-285
  6. Platelet and Megakaryocyte Analysis

    1. Front Matter
      Pages 311-311
    2. Yaping Shou, Mortimer Poncz
      Pages 347-354
  7. Back Matter
    Pages 355-368

About this book


In Hemostasis and Thrombosis Protocols, leading experimentalists describe in detail their proven, cutting-edge methods for research on hemostasis and thrombosis, as well as their diagnostics. The techniques range from widely used basic assays to methods that are specialized for mutational analysis and specific disorders. Readily reproducible, these powerful methods can be used to screen for such inherited disorders as hemophilia A and B, von Willebrands Disease, Factor XI and antithrombin deficiency, protein S deficiency, factor V Leiden mutation, and other problems. The protocols reflect the many major advances that have occurred in our understanding of the molecular genetics of normal hemostasis and it variants, as well as of the coagulation cascade itself.

Suitable for both diagnostic and research laboratories, Hemostasis and Thrombosis Protocols enables experienced and novice investigators alike readily to master the complexities of research on molecular hemostasis and thrombosis, as well as work toward the development of productive new molecular diagnostics.

Editors and affiliations

  • David J. Perry
    • 1
  • K. J. Pasi
    • 1
  1. 1.Royal Free HospitalLondonUK

Bibliographic information

  • DOI
  • Copyright Information Humana Press 1999
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-0-89603-419-8
  • Online ISBN 978-1-59259-248-7
  • Series Print ISSN 1543-1894
  • Series Online ISSN 1940-6037
  • Buy this book on publisher's site