Renal Cancer

Methods and Protocols

  • Jack H. Mydlo

Part of the Methods in Molecular Medicine™ book series (MIMM, volume 53)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Introduction

    1. Front Matter
      Pages 1-1
    2. Paul Russo
      Pages 3-33
    3. David J. Grignon
      Pages 35-51
  3. In Vitro Experimental Techniques

    1. Front Matter
      Pages 53-53
    2. William W. Zhang, Laurence H. Klotz
      Pages 55-67
    3. Joseph C. Presti Jr.
      Pages 69-80
    4. Raffaele Baffa, Coleen M. Calviello, Teresa Druck, Leonard G. Gomella
      Pages 81-93
    5. Kenneth J. Pienta, Jeffrey F. Williams
      Pages 95-100
    6. Alexander Kugler, Paul Thelen, Rolf-Hermann Ringert
      Pages 139-150
    7. Greg L. Griewe, Robert Dean, Wei Zhang, Isabella A. Sesterhenn, Shiv Srivastava, Judd W. Moul
      Pages 165-173
    8. Leslie Kushner, Pui Yan Chiu, Peter Pinto, Gary Hal Weis
      Pages 175-191
    9. Allen Chernoff, Viera Kasparcova, W. Marston Linehan, Catherine A. Stolle
      Pages 193-216
    10. Robert L. Vessella, D. Scott Wilbur, Kent Buhler, Paul H. Lange
      Pages 217-242
  4. In Vivo Experimental Techniques

    1. Front Matter
      Pages 243-243
    2. David M. Nanus, Dov Engelstein
      Pages 245-253
    3. Nobuyasu Nishisaka, Philo Morse, Richard F. Jones, Ching Y. Wang, Gabriel P. Haas
      Pages 255-264
    4. Jack H. Mydlo
      Pages 265-275
    5. Steven C. Campbell, Frank K. Reiher, Norman D. Smith Jr.
      Pages 277-298
  5. Clinical Trials and Experiments

    1. Front Matter
      Pages 299-299
    2. Wilbur B. Bowne, William G. Hawkins, Jonathan J. Lewis
      Pages 313-321
    3. Egbert Oosterwijk
      Pages 323-341
    4. Robert G. Uzzo, Vladimir Kolenko, Andrew C. Novick, James H. Finke
      Pages 361-376
    5. Ralph Madeb, Dov Pode, Ofer Nativ
      Pages 385-399
  6. Wilbur B. Browne, William G. Hawkins, Jonathan J. Lewis
    Pages E1-E1
  7. Back Matter
    Pages 401-403

About this book


Because renal cancer can be managed successfully only when localized, there is a great need to develop new treatments for patients with advanced or metastatic disease. In Renal Cancer: Methods and Protocols, Jack H. Mydlo, MD, and a panel of leading clinicians and researchers review every aspect of the latest surgical, medical, and immunological therapies that can be used in the diagnosis and treatment of renal cancer. These broadly experienced investigators also present a practical account of their best basic research methods, including the use of reverse transcriptase PCR combined with genomic hybridization, cadherin, and metalloproteinase expression to reveal important factors in the detection, staging, aggressiveness, and treatment of this disease. Gene therapy, the generation of monoclonal antibodies, and the use of interferon alpha, GM-CSF, and IL-6 are also discussed. In vivo assays are provided for analyzing angiogenesis, anti-angiogenesis, and general renal tumor biology as a prelude to human clinical trials.
Comprehensive and pioneering, Renal Cancer: Methods and Protocols offers urologists, medical oncologists, laboratory investigators, and pathologists a practical collection of the major cutting-edge techniques and therapies for renal cancer today, together with a view of the highly promising future of gene therapy.

Editors and affiliations

  • Jack H. Mydlo
    • 1
  1. 1.Temple University School of MedicinePhiladelphia

Bibliographic information

  • DOI
  • Copyright Information Humana Press 2001
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Protocols
  • Print ISBN 978-0-89603-828-8
  • Online ISBN 978-1-59259-144-2
  • Series Print ISSN 1543-1894
  • Series Online ISSN 1940-6037
  • Buy this book on publisher's site