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Ovarian Cancer

Methods and Protocols

Part of the book series: Methods in Molecular Medicine (MIMM, volume 39)

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Table of contents (89 protocols)

  1. Model Systems

    1. In Vitro Invasion Assays

      • Setsuko K. Chambers
      Pages 179-185
    2. p53Transfectants in Ovarian Cancer

      • Faina Vikhanskaya, Massimo Broggini
      Pages 187-191
    3. Estrogen-Responsive Ovarian Cancer Xenografts

      • Alison A. Ritchie, Simon P. Langdon
      Pages 193-198
  2. Cytogenetics

    1. Front Matter

      Pages 205-269
    2. Interphase Cytogenetics in Paraffin-Embedded Ovarian Tissue

      • Susann Neubauer, Thomas Liehr
      Pages 223-228
    3. Gene Amplification of c-erbB-2 Detected by FISH

      • S. Robert Young, Wei-Hua Liu, Zong-Ren Wang
      Pages 237-245
    4. Quantitation of FISH Signals in Archival Tumors

      • Amanda D. Watters, John M. S. Bartlett
      Pages 253-260
  3. Molecular Genetic Imbalances in Ovarian Tumors

    1. Front Matter

      Pages 271-395
    2. Molecular Genetics of Ovarian Cancer

      • William Foulkes, Andrew N. Shelling
      Pages 273-290
    3. RFLP Molecular Analysis of the Urokinase-Type Plasminogen Activator Gene

      • Bernd Muehlenweg, Andreas Schnelzer, Beyhan Türkmen, Ernst Lengyel, Ute Reuning, Henner Graeff et al.
      Pages 299-306
    4. PCR Microsatellite Analysis of LOH in Ovarian Tumors

      • Jayne Devlin, Margaret A. Knowles
      Pages 307-314
    5. SSCP and Sequence Analysis of p53 Mutations in Ovarian Tumors

      • Anil K. Sood, Richard E. Buller
      Pages 323-328

About this book

If there is one aspect of current cancer research that represents a major ch- lenge in both novice and experienced researchers, it is the rapid advance in our understanding of the disease. Researchers can be required to switch from analysis of gene expression to kinetics of protein activation, from genetic studies to the analysis of protein funtion. Cancers are highly complex disease systems and researchers aiming to understand the functioning of cancer systems require access to a wide range of laboratory techiques from a broad range of research disciplines. Increasingly, however, published methods are incomplete or refer back to a series of previous publications each containing only a small part of the complete pro- col. The aim of Ovarian Cancer: Methods and Protocols is to provide for ovarian cancer researchers in the first instance, a laboratory handbook that will facilitate research into cancer systems by providing a series of expert protocols, with proven efficacy, across a broad range of technical expertise. Thus, there are sections on tumor genetics and cellular signal transduction, as well as sections on apoptosis and RNA analysis. The value of Ovarian Cancer: Methods and Protocols to the ovarian cancer researcher will, I trust, be considerably enhanced by (1) the provision of a series of overviews relating to the biology, diagnosis, and treatment of this important neoplasm, and (2) the provision of a series of technical overviews introducing each part that provides an expert review of the applications and pitfalls of the various techniques included.

Editors and Affiliations

  • Department of Surgery, University of Glasgow, Glasgow, Scotland

    John M. S. Bartlett

Bibliographic Information

  • Book Title: Ovarian Cancer

  • Book Subtitle: Methods and Protocols

  • Editors: John M. S. Bartlett

  • Series Title: Methods in Molecular Medicine

  • DOI: https://doi.org/10.1385/1592590713

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Humana Press 2001

  • Hardcover ISBN: 978-0-89603-583-6Published: 10 September 2000

  • Softcover ISBN: 978-1-4899-4396-5Published: 29 November 2013

  • eBook ISBN: 978-1-59259-071-1Published: 02 February 2008

  • Series ISSN: 1543-1894

  • Series E-ISSN: 1940-6037

  • Edition Number: 1

  • Number of Pages: XXI, 817

  • Topics: Oncology

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access