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Complement Methods and Protocols

  • B. Paul Morgan
Book

Part of the Methods in Molecular Biology book series (MIMB, volume 150)

Table of contents

  1. Front Matter
    Pages i-ix
  2. B. Paul Morgan
    Pages 1-13
  3. Claire L. Harris
    Pages 83-101
  4. Antti Väkevä, Seppo Meri
    Pages 113-121
  5. Juha Hakulinen, Seppo Meri
    Pages 123-129
  6. O. Brad Spiller
    Pages 131-137
  7. Ann Orren
    Pages 139-158
  8. Kevin A. Davies, Peter Norsworthy
    Pages 173-192
  9. Reinhard Würzner
    Pages 193-201
  10. Julian T. Nash, Kevin A. Davies
    Pages 203-214
  11. Anne E. Bygrave, Marina Botto
    Pages 215-228
  12. Stuart Linton
    Pages 229-247
  13. Back Matter
    Pages 249-268

About this book

Introduction

Although the complement system-a vital part of the body's defense against bacteria-was discovered more than a century ago, its study has undergone a renaissance with the identification of its regulatory molecules and the realization that these molecules can be used therapeutically. In Complement Methods and Protocols, B. Paul Morgan and a team of expert laboratorians present a comprehensive set of readily reproducible methods to study this critical system. These cutting-edge techniques are suitable both for the basic scientist interested in understanding complement's mechanisms of activation and for the clinical scientist wishing to quantify its activation, and range from the purification of its components to generating complement-deficient mice by gene deletion. Additional techniques presented include procedures for the analysis of complement function, for the study of its regulators, for detection of its activation in vivo, and for the identification of its autoantibodies.
Comprehensive and cutting-edge, Complement Methods and Protocols offers today's basic and clinical investigators powerful tools for the analysis of the role of complement in human pathophysiology and disease, as well as its therapeutic regulation.

Editors and affiliations

  • B. Paul Morgan
    • 1
  1. 1.Department of Medical BiochemistryUniversity of Wales College of MedicineCardiffUK

Bibliographic information

  • DOI https://doi.org/10.1385/159259056X
  • Copyright Information Humana Press 2000
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-0-89603-654-3
  • Online ISBN 978-1-59259-056-8
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site