Computer Analysis of Sequence Data

Part II

  • Annette M. Griffin
  • Hugh G. Griffin

Part of the Methods in Molecular Biology book series (MIMB, volume 25)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Hugh G. Griffin, Annette M. Griffin
    Pages 1-8
  3. Rodger Staden
    Pages 10-26
  4. Rodger Staden
    Pages 37-67
  5. Rodger Staden
    Pages 79-85
  6. Rodger Staden
    Pages 113-124
  7. Rodger Staden
    Pages 155-170
  8. John H. McVey
    Pages 171-179
  9. Susan E. Douglas
    Pages 181-194
  10. Sue A Olson
    Pages 203-214
  11. Sue A. Olson
    Pages 227-236
  12. Sue A Olson
    Pages 237-246
  13. Michael Gribskov
    Pages 247-266
  14. Aiala Reizer, Milton H. Saier Jr, Jonathan Reizer
    Pages 295-305
  15. Jotun Hein
    Pages 349-364
  16. Cary O’Donnell
    Pages 391-402
  17. Cary O’Donnell
    Pages 403-412
  18. Catherine M. Rice, Graham N.
    Pages 413-424
  19. Back Matter
    Pages 425-433

About this book


DNA sequencing has become increasingly efficient over the years, resulting in an enormous increase in the amount of data gener­ ated. In recent years, the focus of sequencing has shifted, from being the endpoint of a project, to being a starting point. This is especially true for such major initiatives as the human genome project, where vast tracts of DNA of unknown function are sequenced. This sheer volume of available data makes advanced computer methods essen­ tial to analysis, and a familiarity with computers and sequence analy­ sis software a vital requirement for the researcher involved with DNA sequencing. Even for nonsequencers, a familiarity with sequence analysis software can be important. For instance, gene sequences already present in the databases can be extremely useful in the design of cloning and genetic manipulation experiments. This two-part work on Computer Analysis of Sequence Data is designed to be a practical aid to the researcher who uses computers for the acquisition, storage, or analysis of nucleic acid (and/or pro­ tein) sequences. Each chapter is written such that a competent scien­ tist with basic computer literacy can carry out the procedure successfully at the first attempt by simply following the detailed prac­ tical instructions that have been described by the author. A Notes section, which is included at the end of each chapter, provides advice on overcoming the common problems and pitfalls sometimes encoun­ tered by users of the sequence analysis software.

Authors and affiliations

  • Annette M. Griffin
    • 1
  • Hugh G. Griffin
    • 1
  1. 1.Institute of Food Research, Norwich Research ParkNorwichEngland

Bibliographic information

  • DOI
  • Copyright Information Humana Press 1994
  • Publisher Name Springer, Totowa, NJ
  • eBook Packages Springer Protocols
  • Print ISBN 978-0-89603-276-7
  • Online ISBN 978-1-59259-512-9
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site