Transgenesis Techniques

Principles and Protocols

  • David Murphy
  • David A. Carter

Part of the Methods in Molecular Biology™ book series (MIMB, volume 18)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Introduction and Topical Reviews

  3. Transgenesis in Invertebrate and Lower Vertebrate Species

    1. Mark O’Connor, William Chia
      Pages 75-85
    2. Hong-Woo Khoo, Lay-Hong Ang, Hueh-Bin Lim
      Pages 87-94
  4. Transgenesis in the Mouse

    1. David Murphy, David A. Carter
      Pages 111-114
    2. David Murphy, David A. Carter, Duncan R. Smith
      Pages 115-118
    3. Duncan R. Smith, David Murphy
      Pages 119-123
    4. David Murphy
      Pages 131-134
    5. David A. Carter
      Pages 135-136
    6. David Murphy
      Pages 137-140
    7. David Murphy
      Pages 177-178
    8. David A. Carter
      Pages 179-182
    9. Kimball O. Pomeroy
      Pages 239-243
  5. Transgenesis in the Rat

    1. Chiew-Hun Phang
      Pages 253-256
    2. Chiew-Hun Phang
      Pages 257-259
    3. Chiew-Hun Phang
      Pages 261-263
    4. Chiew-Hun Phang
      Pages 265-268
    5. Kimball O. Pomeroy
      Pages 269-270
  6. Transgenesis in a Domestic Species-The Sheep

    1. Colin D. Nancarrow, James T. A. Marshall, Kevin A. Ward
      Pages 273-303
    2. Kimball O. Pomeroy
      Pages 305-306
  7. Genomic Analysis of Transgenic Animals

    1. David Murphy
      Pages 309-312
    2. David Murphy
      Pages 313-315
    3. Duncan R. Smith, David Murphy
      Pages 323-327
  8. Expression Analysis of Transgenic Animals

    1. David Murphy
      Pages 337-340
    2. David Murphy
      Pages 341-343
    3. Peter Koopman
      Pages 345-353
    4. David Murphy
      Pages 355-361
    5. Duncan R. Smith
      Pages 363-372
    6. Duncan R. Smith
      Pages 373-378
    7. Judith McNiff Funkhouser
      Pages 379-393
    8. Judith McNiff Funkhouser
      Pages 395-405
    9. Kum Fai Chooi
      Pages 407-411
    10. Kum Fai Chooi
      Pages 413-417
    11. Karen Pardy
      Pages 419-424

About this book


Over the past twenty years, the disciplines of cellular and molecular biology have generated a bounty of information pertaining to the understanding of the structure and function of eukaryotic cells . It is now recognized that individual cells regulate their activities in response to a multitude of external signals ; that external signals, a- ing through a limited number of second messenger systems, modulate the cell's pattern of gene expression; and that the cohort of genes available for regulation is dependent upon the developmental history of the cell. Extrapolating these truths to the whole organism is a challenge that has been met by an increasing number of investigators . The wealth of information that molecular and cell biology has provided us with is now being integrated into an understanding of whole t- sues, organs, and organisms. Without such an integration, the molecular information will be nothing more than a confusing catalog of sequences and structures. Central to this project will be the app- cation of the powerful new techniques described in Transgenesis Techniques: Principles and Protocols .

Editors and affiliations

  • David Murphy
    • 1
  • David A. Carter
    • 1
  1. 1.National University of SingaporeRepublic of Singapore

Bibliographic information

  • DOI
  • Copyright Information Humana Press 1993
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-0-89603-245-3
  • Online ISBN 978-1-59259-505-1
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site