Overview
- The first book to provide detailed protocols on human tissue dissection, sample processing and molecular analysis combined with substantial background information
- Includes supplementary material: sn.pub/extras
Part of the book series: Principles and Practice (PRINCIPLES)
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Table of contents (11 chapters)
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Front Matter
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Clinkal Issues and Tissue Processing
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Methods of Tissue Microanalysis
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Molecular Analysis of Microdissected Samples
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Back Matter
Keywords
About this book
The book provides an updated overview of molecular analysis of human tissues, and the impact this analysis has on diagnosis and prognosis of human diseases. Special emphasis is placed on human cancer and the future directions of the field. Methods of handling clinical tissue samples, including the impact of handling on subsequent molecular analysis, are also discussed. In addition, detailed protocols for molecular analysis of DNA, RNA and protein, with special emphasis on molecular analysis of highly complex human tissue samples containing mixtures of cell populations, are provided.
Reviews
From the reviews:
"This book, divided into four sections, provides an updated overview of the molecular analysis of human tissues … . Special emphasis is placed on human cancer and the future directions of the field. … The detailed protocols make this book particularly useful for scientists and clinicians interested in the analysis of tissue samples." (CLI – Clinical Laboratory International, Vol. 29 (5), 2005)
Editors and Affiliations
About the editors
Michael Emmert-Buck, MD, PhD is Chief of the Pathogenetics Unit, Laboratory of Pathology, NCI. He received his MD and PhD degrees from Wayne State University and completed his training in anatomic pathology at the NCI. Dr. Emmert-Buck became Chief of the Pathogenetics Unit in 1996.
Rodrigo Chuaqui, MD is the Head of Prostate Research Studies in the Pathogenetics Unit, Laboratory of Pathology, NCI. He received his MD and his training in Anatomic Pathology at the Catholic University, Santiago, Chile, becoming a staff member in the Dept. of Pathology at this University in 1992. In 2000, Dr. Chuaqui joined the NCI, in the Pathogenetics Unit.
John Gillespie, MD is the Head of the Clinical Division of the Pathogenetics Unit, Laboratory of Pathology, NCI. He received his MD and completed his training in Anatomic and Clinical Pathology at the George Washington University. He is a Diplomat of the American Board of Pathology combined Anatomic and Clinical Pathology. In 1997, Dr Gillespie joined the NCI, Pathogenetics Unit.
Bibliographic Information
Book Title: Dissecting the Molecular Anatomy of Tissue
Editors: Michael R. Emmert-Buck, John W. Gillespie, Rodrigo F. Chuaqui
Series Title: Principles and Practice
DOI: https://doi.org/10.1007/b137665
Publisher: Springer Berlin, Heidelberg
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer-Verlag Berlin Heidelberg 2005
Hardcover ISBN: 978-3-540-22006-0Published: 26 November 2004
Softcover ISBN: 978-3-642-06033-5Published: 21 October 2010
eBook ISBN: 978-3-540-26482-8Published: 20 November 2005
Series ISSN: 1866-914X
Series E-ISSN: 1866-9158
Edition Number: 1
Number of Pages: XVIII, 230
Topics: Cell Biology, Immunology, Biochemistry, general, Anatomy, Cancer Research