Functional Ultrastructure

An Atlas of Tissue Biology and Pathology

  • Margit Pavelka
  • Jürgen Roth

About this book

Introduction

The period between 1950 and 1980 were the golden It also provides unique insights into how pathological years of transmission electron microscopy and pro- processes affect cell organization. duced a plethora of new information on the structure of This information is vital to current work in which cells that was coupled to and followed by biochemical the emphasis is on integrating approaches from p- and functional studies. TEM was king and each micro- teomics, molecular biology, molecular imaging and graph of a new object produced new information that physiology, and pathology to understand cell functions led to new insights on cell and tissue organization and and derangements in disease. In this current era, there is their functions. The quality of data represented by the a growing tendency to substitute modern light mic- images of cells and tissues had been perfected to a very scopic techniques for electron microscopy because it is high level by the great microscopists of the era including less technically demanding and is more readily available Palade, Porter, Fawcett, Sjostrand, Rhodin and many to researchers. This atlas reminds us that the infor- others. At present, the images that we see in leading tion obtained by electron microscopy is invaluable and journals for the most part do not reach the same techni- has no substitute.

Keywords

ATP Antigen DNA Glycogen Oligosaccharid biosynthesis cell cell biology cytology electron microscopy histology matrix molecular biology proteins tissue

Authors and affiliations

  • Margit Pavelka
    • 1
  • Jürgen Roth
    • 2
  1. 1.Institut für Histologie und Embryologie, Abteilung für Zellbiologie und UltrastrukturforschungMedizinische Universität Wien, Zentrum für Anatomie und ZellbiologieViennaAustria
  2. 2.Abteilung für Zell- und MolekularpathologieUniversität ZürichZurichSwitzerland

Bibliographic information

  • DOI https://doi.org/10.1007/b137527
  • Copyright Information Springer-Verlag/Wien 2005
  • Publisher Name Springer, Vienna
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-211-83564-7
  • Online ISBN 978-3-211-26392-1
  • About this book