Hughes Syndrome

Antiphospholipid Syndrome

  • M. A. Khamashta

Table of contents

  1. Front Matter
    Pages i-xxi
  2. Clinical Aspects

    1. Front Matter
      Pages 1-1
    2. M. A. Khamashta
      Pages 3-8
    3. Michelle Petri
      Pages 22-28
    4. Carlomaurizio Montecucco, Roberto Caporali
      Pages 29-40
    5. Josep Font, Ricard Cervera
      Pages 41-52
    6. Debendra Pattanaik, Robin L. Brey
      Pages 53-67
    7. Carlos A. Battagliotti
      Pages 86-98
    8. Mary-Carmen Amigo, Romeo García-Torres
      Pages 99-111
    9. Shirish R. Sangle, David P. D’Cruz
      Pages 112-116
    10. Jean-Charles Piette, Beverley J. Hunt
      Pages 117-126
    11. Maria G. Tektonidou, Haralampos M. Moutsopoulos
      Pages 127-139
    12. Elias Toubi, Aharon Kessel
      Pages 140-146
    13. Cristina Castañon, Pedro A. Reyes
      Pages 147-154
    14. Tonia L. Vincent, Charles G. Mackworth-Young
      Pages 155-170
    15. H. Michael Belmont
      Pages 171-180
    16. T. Flint Porter, Robert M. Silver, D. Ware Branch
      Pages 181-195
    17. Lisa R. Sammaritano
      Pages 196-208

About this book


The second edition of Hughes Syndrome: Antiphospholipid Syndrome addresses the complete range of conditions produced by this common disorder which is also known as APS or "sticky blood" syndrome. APS is one of the main causes of strokes (40%), leg deep vein thrombosis, and recurrent miscarriages in women. It is an important risk factor for thrombosis in women taking the oral contraceptive pill.

The effects of this syndrome were found initially in thrombosis, obstetrics (APS is the most common treatable cause of recurrent pregnancy loss) and neurology. Its impact is now felt in a diverse range of conditions. These include surgery (graft rejection), orthopedics (avascular necrosis, DVT), psychiatry (memory loss), cardiology (pulmonary hypertension, valvular disease, angina), ENT (vertigo), pediatrics (young strokes, epilepsy) to name but a few.

This new and updated text reflects the growth in published literature on APS and the widening ramifications of the disease. APS is a multi-specialty disease and is of increasing interest to obstetricians, rheumatologists, hematologists, dermatologists, neurologists and immunologists.


Antiphospholipid Syndrome Hughes Syndrome Sticky Blood Syndrome hypertension infertility neurology psychiatry transplantation

Editors and affiliations

  • M. A. Khamashta
    • 1
  1. 1.Lupus Research UnitSt Thomas’ HospitalLondonUK

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag London Limited 2006
  • Publisher Name Springer, London
  • eBook Packages Medicine
  • Print ISBN 978-1-85233-873-2
  • Online ISBN 978-1-84628-009-2
  • About this book