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Small-Animal SPECT Imaging

  • Book
  • © 2005

Overview

Editors:
  1. Matthew A. Kupinski

    1. Optical Science Center, The University of Arizona, Tucson, USA

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  2. Harrison H. Barrett

    1. Optical Science Center, The University of Arizona, Tucson, USA

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    You can also search for this editor in PubMed   Google Scholar

  • Small-animal SPECT is a relatively new imaging tool that can aid in drug development, drug research, molecular imaging, and imaging science

  • Presents cutting-edge research in these areas as well as an overview of modern small-animal SPECT systems. Everything from the basic physics of SPECT imaging to animal studies are presented. Sections on animal handling, image quality assessment, and reconstruction algorithms are also included to help researchers design and run their own studies

  • Includes supplementary material: sn.pub/extras

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Table of contents (25 chapters)

  1. Front Matter

    Pages i-xxii
    Download chapter PDF

  2. Biomedical Significance of Small-Animal Imaging

    • James M. Woolfenden, Zhonglin Liu
    Pages 1-8

  3. Detectors for Small-Animal SPECT I

    • Harrison H. Barrett, William C. J. Hunter
    Pages 9-48

  4. Detectors for Small-Animal SPECT II

    • Harrison H. Barrett
    Pages 49-86

  5. The Animal in Animal Imaging

    • Gail Stevenson
    Pages 87-100

  6. Objective Assessment of Image Quality

    • Matthew A. Kupinski, Eric Clarkson
    Pages 101-114

  7. SPECT Imager Design and Data-Acquisition Systems

    • Lars R. Furenlid, Yi-Chun Chen, Hyunki Kim
    Pages 115-138

  8. Computational Algorithms in Small-Animal Imaging

    • Donald W. Wilson
    Pages 139-162

  9. Reconstruction Algorithm with Resolution Deconvolution in a Small-Animal PET Imager

    • Edward N. Tsyganov, Alexander I. Zinchenko, Nikolai V. Slavine, Pietro P. Antich, Serguei Y. Seliounine, Orhan K. Oz et al.
    Pages 163-175

  10. Estimates of Axial and Transaxial Resolution for One-, Two-, and Three-Camera Helical Pinhole SPECT

    • Scott D. Metzler, Ronald J. Jaszczak
    Pages 177-182

  11. Pinhole Aperture Design for Small-Animal Imaging

    • Chih-Min Hu, Jyh-Cheng Chen, Ren-Shyan Liu
    Pages 183-187

  12. Comparison of CsI(Ti) and Scintillating Plastic in a Multi-Pinhole/CCD-Based Gamma Camera for Small-Animal Low-Energy SPECT

    • Edmond Richer, Matthew A. Lewis, Billy Smith, Xiufeng Li, Serguei Seliounine, Ralph P. Mason et al.
    Pages 189-194

  13. Calibration of Scintillation Cameras and Pinhole SPECT Imaging Systems

    • Yi-Chun Chen, Lars R. Furenlid, Donald W. Wilson, Harrison H. Barrett
    Pages 195-201

  14. Imaging Dopamine Transporters in a Mouse Brain with Single-Pinhole SPECT

    • Jan Booij, Gerda Andringa, Kora de Bruin, Jan Habraken, Benjamin Drukarch
    Pages 203-207

  15. A Micro-SPECT/CT System for Imaging of AA-Amyloidosis in Mice

    • Jens Gregor, Shaun Gleason, Stephen Kennel, Michael Paulus, Alan Solomon, Philip Hawkins et al.
    Pages 209-213

  16. Feasibility of Micro-SPECT/CT Imaging of Atherosclerotic Plaques in a Transgenic Mouse Model

    • Benjamin M. W. Tsui, Yuchuan Wang, Yujin Qi, Stacia Sawyer, Eric C. Frey, Stan Majewski et al.
    Pages 215-223

  17. Effect of Respiratory Motion on Plaque Imaging in the Mouse Using Tc-99m Labeled Annexin-V

    • William P. Segars, Yuchuan Wang, Benjamin M. W. Tsui
    Pages 225-231

  18. Calibration and Performance of the Fully Engineered YAP-(S)PET Scanner for Small Rodents

    • Alberto Del Guerra, Nicola Belcari, Deborah Herbert, Alfonso Motta, Angela Vaiano, Giovanni Di Domenico et al.
    Pages 233-237

  19. A Small-Animal SPECT Imaging System Utilizing Position Tracking of Unanesthetized Mice

    • Andrew G. Weisenberger, Brian Kross, Stan Majewski, Vladimir Popov, Mark F. Smith, Benjamin Welch et al.
    Pages 239-243

  20. A Multidetector High-Resolution SPECT/CT Scanner with Continuous Scanning Capability

    • Tobias Funk, Mingshan Sun, Andrew B. Hwang, James Carver, Steve Thompson, Kevin B. Parnham et al.
    Pages 245-250
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Keywords

About this book

Small-Animal SPECT Imaging is an edited work derived from the first workshop on Small-Animal SPECT Imaging held January 14-16, 2004 at the University of Arizona, Tucson, AZ, USA. The overall goal of the meeting and therefore this volume is to promote information exchange and collaboration between the research groups developing systems for small-animal applications. Topics include the biomedical significance of small-animal imaging, an overview of detector technologies including scintillation cameras and semi-conductor arrays, imager design and data acquisition systems, animal handling and anesthesia issues, objective assessment of image quality, and system modeling and reconstruction algorithms.

Editors and Affiliations

  • Optical Science Center, The University of Arizona, Tucson, USA

    Matthew A. Kupinski, Harrison H. Barrett

Bibliographic Information

  • Book Title: Small-Animal SPECT Imaging

  • Editors: Matthew A. Kupinski, Harrison H. Barrett

  • DOI: https://doi.org/10.1007/b107067

  • Publisher: Springer New York, NY

  • eBook Packages: Engineering, Engineering (R0)

  • Copyright Information: Springer-Verlag US 2005

  • Hardcover ISBN: 978-0-387-25143-1Published: 21 June 2005

  • Softcover ISBN: 978-1-4419-3774-2Published: 08 December 2010

  • eBook ISBN: 978-0-387-25294-0Published: 27 May 2007

  • Edition Number: 1

  • Number of Pages: XXII, 294

  • Number of Illustrations: 123 b/w illustrations

  • Topics: Biomedical Engineering and Bioengineering, Biomedicine general, Cancer Research, Cardiology, Human Genetics

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