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  • © 2023

Multistep Continuous Flow Synthesis of Fine Chemicals with Heterogeneous Catalysts

Authors:

  • Nominated as an outstanding PhD thesis by The University of Tokyo

  • Presents a new synthetic strategy design, suitable for multistep continuous-flow synthesis

  • Explains the synthesis of active pharmaceutical ingredients via multistep flow catalysis

Part of the book series: Springer Theses (Springer Theses)

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Softcover Book USD 199.99
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About this book

This book describes the development of two kinds of continuous-flow transformation using heterogeneous catalysts, and explains how they can be applied in the multistep synthesis of active pharmaceutical ingredients. It demonstrates and proves that fine chemicals can be synthesized under continuous-flow conditions using heterogeneous catalysis alone. Importantly, the book also proposes a general concept and strategy for achieving multistep flow synthesis and developing heterogeneous catalysts, and shows that commercially available anion exchange resin can be used as a water-tolerant strong base catalyst for various types of continuous-flow aldol-type reaction. Reviewing the state of the art in heterogeneous catalysis in flow chemistry – a “hot topic” and rapidly developing area of organic synthesis – the book will provide readers with a deeper understanding of fine chemical flow synthesis and its future prospects. 

Keywords

  • Continuous-flow
  • Heterogeneous Catalyst
  • Hydrogenation
  • C-­C Bond Forming Reaction
  • Fine Chemical Synthesis

Authors and Affiliations

  • Department of Chemistry, School of Science, The University of Tokyo, Tokyo, Japan

    Yuki Saito

Bibliographic Information

Buy it now

Buying options

eBook USD 149.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 199.99
Price excludes VAT (USA)
This title has not yet been released. You may pre-order it now and we will ship your order when it is published on 15 Dec 2023.
  • Compact, lightweight edition
  • Free shipping worldwide - see info
Hardcover Book USD 199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access