© 2019

Autophagy: Biology and Diseases

Basic Science

  • Zheng-Hong Qin

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1206)

Table of contents

  1. Front Matter
    Pages i-xv
  2. History and Current Status of Autophagy Research

    1. Front Matter
      Pages 1-1
    2. Rui Sheng, Zheng-Hong Qin
      Pages 3-37
  3. Regulation of Autophagy

    1. Front Matter
      Pages 39-39
    2. Wen Li, Lining Zhang
      Pages 41-65
    3. Ying Wang, Hongbing Zhang
      Pages 67-83
    4. Yanjun Li, Yingyu Chen
      Pages 85-108
    5. Hai-Dong Xu, Zheng-Hong Qin
      Pages 109-126
    6. Wanglai Hu, Song Chen, Rick F. Thorne, Mian Wu
      Pages 127-149
    7. Yang-Xi Hu, Xiao-Shuai Han, Qing Jing
      Pages 151-166
    8. Zhihao Qi, Linxi Chen
      Pages 167-177
    9. Qi Gao
      Pages 179-198
    10. Honghong Yao, Bing Han, Yuan Zhang, Ling Shen, Rongrong Huang
      Pages 199-220
    11. Li-Fang Hu
      Pages 221-236
    12. Rui Wang, Guanghui Wang
      Pages 237-259
    13. Nan Zhang, Ying Zhao
      Pages 261-271
    14. Min Wei, Wei-Dong Le
      Pages 273-286
    15. Lifeng Pan, Jianping Liu, Ying Li
      Pages 287-326
  4. Biological Function of Autophagy

    1. Front Matter
      Pages 327-327
    2. Jie Yang, Ruimin Zhou, Zhenyi Ma
      Pages 329-357

About this book


This book series consists of 3 volumes covering the basic science (Volume 1), clinical science (Volume 2) and the technology and methodology (Volume 3) of autophagy.

Volume 1 focuses on the biology of autophagy, including the signaling pathways, regulating processes and biological functions. Autophagy is a fundamental physiological process in eukaryotic cells. It not only regulates normal cellular homeostasis, and organ development and function, but also plays an important role in the pathogenesis of a wide range of human diseases. Thanks to the rapid development of molecular biology and omic technologies, research on autophagy has boomed in recent decades, and more and more cellular and animal models and state-of the-art technologies are being used to shed light on the complexity of signaling networks involved in the autophagic process. Further, its involvement in biological functions and the pathogenesis of various diseases has attracted increased attention around the globe. Presenting cutting-edge knowledge, this book series is a useful reference resource for researchers and clinicians who are working on or interested in autophagy.


Autophagy Metabolism Longevity Signal Transduction Epigenetic Regulation Protein Modification Immune Responses

Editors and affiliations

  • Zheng-Hong Qin
    • 1
  1. 1.Jiangsu Key Laboratory of Neuropsychiatric Diseases, Department of Pharmacology and Laboratory of Aging and Nervous DiseasesCollege of Pharmaceutical Sciences of Soochow UniversitySuzhouChina

About the editors

Dr. Zheng-Hong Qin is a Professor of Pharmacology at the School of Pharmaceutical Sciences, Soochow University. He is also the Director of the Laboratory of Aging and Nervous Diseases, Soochow University. Prof. Qin holds positions in several academic societies, including Associate Director of the Anti-aging Branch of the Chinese Society of Gerontology and Geriatrics, and committee member of the Biochemical and Molecular Pharmacology Branch and Neuro- and Psycho-pharmacology Branch of the Chinese Neuroscience Society. He serves on the editorial board of Acta Pharmacologica Sinica. Prof. Qin’s research focuses on aging and age-related neurological disorders and drug development from venoms. A pioneer in the field of autophagy in China, he has published more than 200 articles and was listed as the most-cited Chinese scholar in 5 consecutive years, from 2014 to 2018. 

Bibliographic information

  • Book Title Autophagy: Biology and Diseases
  • Book Subtitle Basic Science
  • Editors Zheng-Hong Qin
  • Series Title Advances in Experimental Medicine and Biology
  • Series Abbreviated Title Adv Exp Med Biol
  • DOI
  • Copyright Information Science Press and Springer Nature Singapore Pte Ltd. 2019
  • Publisher Name Springer, Singapore
  • eBook Packages Biomedical and Life Sciences Biomedical and Life Sciences (R0)
  • Hardcover ISBN 978-981-15-0601-7
  • Softcover ISBN 978-981-15-0604-8
  • eBook ISBN 978-981-15-0602-4
  • Series ISSN 0065-2598
  • Series E-ISSN 2214-8019
  • Edition Number 1
  • Number of Pages XV, 727
  • Number of Illustrations 8 b/w illustrations, 83 illustrations in colour
  • Topics Molecular Medicine
    Cell Biology
    Biochemistry, general
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