Molecular Diagnostics in Cancer Patients

  • Kamla Kant Shukla
  • Praveen Sharma
  • Sanjeev Misra

Table of contents

  1. Front Matter
    Pages i-viii
  2. Kamla Kant Shukla, Shrimanjunath Sankanagoudar, Barkha Singhal Sanganeria, Puneet Pareek, Jeevan Ram, Sanjeev Misra et al.
    Pages 1-9
  3. Rajani Rai, Saumyak Gosai, Chinthalapally V. Rao, Vishal Chandra
    Pages 11-25
  4. Ashok Kumar, Ashwani Tandon
    Pages 27-41
  5. Vibhuti Joshi, Arun Upadhyay, Ayeman Amanullah, Ribhav Mishra, Amit Mishra
    Pages 43-72
  6. A. Srivastava, P. Srivastava, A. B. Pant
    Pages 73-88
  7. Rajeshwari Sinha, Sanghamitra Pati
    Pages 89-102
  8. Suraj Pratap, Teresa A. Scordino
    Pages 103-127
  9. Balraj Mittal, Saurabh Yadav
    Pages 129-142
  10. Sandeep Agrawal, Aditi Bhattacharya, Janvie Manhas, Sudip Sen
    Pages 143-155
  11. Shruti Mishra, Vipin Rai, Abhai Kumar, Sushil Kumar Aggarwal, Subash Chandra Gupta
    Pages 157-163
  12. Nuzhat Husain, Azfar Neyaz
    Pages 165-185
  13. Mohammad Kaleem Ahmad, Soumya Srivastava, Abbas Ali Mahdi
    Pages 187-198
  14. Barkha Singhal Sanganeria, Radhieka Misra, Kamla Kant Shukla
    Pages 199-218
  15. A. N. Srivastava, Kirti A. Gautam, S. N. Sankhwar
    Pages 219-235
  16. Anil Kumar Chauhan, Monika Bhardwaj, Pankaj Kumar Chaturvedi
    Pages 293-303
  17. Rajani Rai, Iram Fatima, Katie Essel, Vishal Chandra
    Pages 305-321
  18. Shailendra Dwivedi, Radhieka Misra, Purvi Purohit, Jeewan Ram Vishnoi, Puneet Pareek, Apul Goel et al.
    Pages 323-341

About this book


This book aims to bring together a broad variety of examples of the role of pharmacogenomics in current drug development, uncovering dynamic concentration-dependent drug responses on biological systems to understand pharmacodynamics responses in human cancer where genetic lesions serve as tumor markers and provide a basis for cancer diagnosis. 

The book describes methods and protocols applied in molecular diagnostics. It offers pathologists and researchers providing molecular diagnostic services an array of the most recent and readily accessible reference to compare methods and techniques.  

Highlights include the molecular diagnosis of genetic aberrations by quantitative polymerase reaction (qPCR), sequence-specific oligonucleotide arrays, next-generation sequencing (NGS), CGH arrays-and methodologies directed at the detection of epigenetic events, high-throughput nucleic acid and protein arrays, direct sequencing and FISH-based methodologies, currently used in the diagnosis of solid tumors. The book also includes an innovative line of treatment in relation to the molecular prognosis, diagnosis and pharmacogenomics in the actual practice of clinical findings at molecular levels. The book covers the applications of numerous genetic testing methodologies; in approximately the chronological order of discovery and high-throughput diagnosis using advanced genomic approaches to identify such genes, in the search for novel drug targets and/or key determinants of drug reactions. It also promotes a wider understanding of molecular diagnostics among physicians, medical students, and scientists in academics, industry and corporate world.


Molecular Diagnostics in Lung cancer Molecular Diagnostics in Breast cancer Molecular Diagnostics in Skin cancer Molecular Diagnostics in Thyroid cancer Molecular Diagnostics in Uterine cancer

Editors and affiliations

  • Kamla Kant Shukla
    • 1
  • Praveen Sharma
    • 2
  • Sanjeev Misra
    • 3
  1. 1.Department of BiochemistryAll India Institute of Medical SciencesJodhpurIndia
  2. 2.Department of BiochemistryAll India Institute of Medical SciencesJodhpurIndia
  3. 3.Department of Surgical OncologyAll India Institute of Medical SciencesJodhpurIndia

Bibliographic information

  • DOI
  • Copyright Information Springer Nature Singapore Pte Ltd. 2019
  • Publisher Name Springer, Singapore
  • eBook Packages Medicine
  • Print ISBN 978-981-13-5876-0
  • Online ISBN 978-981-13-5877-7
  • Buy this book on publisher's site