Intraocular and Intracranial Pressure Gradient in Glaucoma

  • Ningli Wang

Part of the Advances in Visual Science and Eye Diseases book series (AVSED, volume 1)

Table of contents

  1. Front Matter
    Pages i-xv
  2. Review of the Study of Trans-laminar Cribrosa Pressure Difference

  3. Anatomy and Pathophysiology

    1. Front Matter
      Pages 45-45
    2. Xiaoxia Li, Ningli Wang
      Pages 47-53
    3. Jiawei Wang, Ningli Wang
      Pages 55-57
    4. Xiaoxia Li, Ningli Wang
      Pages 95-98
  4. Methodology

    1. Front Matter
      Pages 99-99
    2. Xiaobin Xie, April Peszel, Feras Kamel Rizeq, Chenyu Sun, Diya Yang, Ningli Wang
      Pages 101-120
    3. Hanruo Liu, Diya Yang, Teng Ma, Wenyuan Shi, Zhu Qiang, Ningli Wang
      Pages 127-133
  5. Basic Experiment and Hypothesis

    1. Front Matter
      Pages 145-145
    2. Chao Dai, Geoffrey Raisman, Ying Li
      Pages 147-152
    3. Da Zhao, Zheng He, Anna Van Koeverden, Algis J. Vingrys, Vickie H. Y. Wong, Jeremiah K. H. Lim et al.
      Pages 159-165
    4. Ruowu Hou, Ningli Wang
      Pages 167-171
    5. Lu Liu, Caixia Lin, Ningli Wang
      Pages 185-188
  6. Clinical Studies and Cases

    1. Front Matter
      Pages 189-189
    2. Nancy J. Newman
      Pages 195-197
    3. Zhen Li, Xuxiang Zhang, Dachuan Liu, Ningli Wang
      Pages 199-203
    4. Ruojin Ren, Hongli Yang, Stuart Gardiner, Christy Hardin, Shaban Demirel, Claude F. Burgoyne
      Pages 205-209
    5. Alon Harris, Josh Gross, Daniele Prada, Brent Siesky, Alice C. Verticchio Vercellin, Lauren Saint et al.
      Pages 225-238
    6. Qing Zhang, Chen Xin, Chunyu Guo, Ye Zhang, Ningli Wang
      Pages 239-244
    7. Xiaobin Xie, Ningli Wang
      Pages 245-247
  7. Biomechanics of Trans-laminar Cribrosa Pressure Difference

    1. Front Matter
      Pages 253-253
    2. Claude F. Burgoyne
      Pages 255-266
  8. Nutrition and POAG

    1. Front Matter
      Pages 281-281
    2. Jinghong Sang, Qian Zhang, Huaizhou Wang, Diya Yang, Ningli Wang
      Pages 287-290
    3. Jing Yu, Jinghong Sang, Ningli Wang
      Pages 291-293

About this book


This book focuses on the characteristic of glaucomatous optic neuropathy and its relationship with cerebrospinal fluid (CSF) pressure. It also explores the potential novel methods to manage glaucoma by adjusting CSF pressure.

This book covers several interesting topics such as why normal tension glaucoma (NTG) patients still develops into glaucoma without high intraocular pressure (IOP); and whether there are factors other than IOP contributing to the pathogenesis of NTG why the role of IOP in the pathogenesis of POAG becomes vague and controversial. This book contains over 40 chapters, including numerous images from clinical patients and experiments on gross anatomy, pathological tissue, and immunohistochemistry, electronic speculum etc. The ophthalmologists and researchers can also benefit from the clinical cases. We hope this book serves as a clinical guidance with practical significant for the understanding, prevention and diagnosis of glaucoma.


Glaucoma Intraocular Pressure Intracranial pressure Trans-laminar cribrosa pressure difference optic neuropahty

Editors and affiliations

  • Ningli Wang
    • 1
  1. 1.Beijing Tongren HospitalCapital Medical UniversityBeijingChina

Bibliographic information

  • DOI
  • Copyright Information Springer Nature Singapore Pte Ltd. 2019
  • Publisher Name Springer, Singapore
  • eBook Packages Medicine
  • Print ISBN 978-981-13-2136-8
  • Online ISBN 978-981-13-2137-5
  • Series Print ISSN 2524-566X
  • Series Online ISSN 2524-5678
  • Buy this book on publisher's site