Overview
- Providing a comprehensive review of the major barriers to HIV cure and vaccine
- Covering the fundamental virology and immunology of HIV
- Discussing the challenges related to development of HIV vaccine and its clinical trials
Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1075)
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Table of contents (13 chapters)
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Front Matter
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HIV Vaccines
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Front Matter
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HIV Cure
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Front Matter
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Keywords
About this book
This book provides a comprehensive review of the major barriers to HIV cure and vaccine. It covers the fundamental virology and immunology leading to HIV transmission, protection from infection and long term HIV persistence on antiretroviral therapy. In addition, strategies being tested to eliminate persistent HIV and the rational design of vaccines to induce protective immunity are covered. This book also discusses the challenges related to the design of clinical trials for testing the safety and efficacy of these innovative approaches. This book will provide a systematic overview and also discuss controversial issues for researchers in virology and immunology, as well as practicing physicians, and scientists in the pharmaceutical industry.
Editors and Affiliations
About the editors
Dr. Linqi Zhang is a professor of Department of Basic Medical Sciences, and the director of Comprehensive AIDS Research Center, Tsinghua University. He is also an adjunct professor of Peking Union Medical College, China. Prof. Zhang was the Chief Scientist for the National Key Basic Research Projects of China “HIV Biology and its Immune Responses”. His research focuses on pathogenesis of HIV-1 and vaccine development against HIV-1. He has published more than 100 research articles on international journals in this field.
Dr. Sharon Lewin is a professor of Medicine at the University of Melbourne and the inaugural director of the Peter Doherty Institute for Infection and Immunity, a joint venture of the University of Melbourne and Royal Melbourne Hospital. She is a consultant physician at the Alfred Hospital and a practitioner fellow funded by the National Health and Medical Research Council of Australia. Prof. Lewin’s research focuses on understanding how HIV persists on antiretroviral therapy, developing early clinical trials to achieve a cure for HIV and understanding how HIV interacts with other viruses such as hepatitis B virus. She has published more than 250 research articles in these fields.
Bibliographic Information
Book Title: HIV Vaccines and Cure
Book Subtitle: The Path Towards Finding an Effective Cure and Vaccine
Editors: Linqi Zhang, Sharon R. Lewin
Series Title: Advances in Experimental Medicine and Biology
DOI: https://doi.org/10.1007/978-981-13-0484-2
Publisher: Springer Singapore
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Nature Singapore Pte Ltd. 2018
Hardcover ISBN: 978-981-13-0483-5Published: 02 August 2018
Softcover ISBN: 978-981-13-4428-2Published: 29 December 2018
eBook ISBN: 978-981-13-0484-2Published: 20 July 2018
Series ISSN: 0065-2598
Series E-ISSN: 2214-8019
Edition Number: 1
Number of Pages: XV, 318
Number of Illustrations: 5 b/w illustrations, 16 illustrations in colour
Topics: Virology, Vaccine, Immunology, Animal Models