Evolution of Atopic Dermatitis in the 21st Century

  • Ichiro Katayama
  • Hiroyuki Murota
  • Takahiro Satoh

Table of contents

  1. Front Matter
    Pages i-vii
  2. Introduction

    1. Front Matter
      Pages 1-1
    2. Kiyoshi Nishioka
      Pages 3-10
  3. Epidemiology

    1. Front Matter
      Pages 11-11
    2. Takumi Takizawa, Akihiro Morikawa, Hirokazu Arakawa
      Pages 13-24
    3. Yasuyuki Sumikawa
      Pages 25-35
    4. Akiko Kijima, Hiroyuki Murota, Ichiro Katayama
      Pages 37-42
  4. Genetics

    1. Front Matter
      Pages 43-43
  5. Etiopathology of AD From Japanese Studies

    1. Front Matter
      Pages 59-59
    2. Hiroyuki Murota, Kosuke Yamaga, Ichiro Katayama
      Pages 61-68
    3. Takashi Hashimoto, Takahiro Satoh
      Pages 69-82
    4. Kenji Izuhara, Satoshi Nunomura, Shoichiro Ohta, Masahiro Ogawa, Yasuhiro Nanri
      Pages 97-112
    5. Hiroyuki Murota, Ichiro Katayama
      Pages 113-124
    6. Tetsuo Shiohara, Yurie Shimoda-Komatsu, Yoshiko Mizukawa, Yuki Hayashida, Yumi Aoyama
      Pages 125-140
    7. Keiji Iwatsuki, Osamu Yamasaki, Shin Morizane
      Pages 141-155
    8. Mayuko Nakano-Tahara, Hiroyuki Murota, Ichiro Katayama
      Pages 157-163
    9. Ichiro Katayama, Kohsuke Yamaga, Hiroyuki Murota
      Pages 165-177
  6. Classification

    1. Front Matter
      Pages 179-179
    2. Yoshiki Tokura
      Pages 181-199
  7. Clinical Manifestations

    1. Front Matter
      Pages 201-201
    2. Hirokazu Arakawa
      Pages 203-213
    3. Aya Takahashi, Hiroyuki Murota, Ichiro Katayama
      Pages 215-227
    4. Ryoji Tanei
      Pages 229-248
    5. Ichiro Katayama
      Pages 249-262
  8. Diagnosis

    1. Front Matter
      Pages 263-263
    2. Hidehisa Saeki
      Pages 265-280
  9. Management

    1. Front Matter
      Pages 281-281
    2. Takahiro Satoh
      Pages 283-287
    3. Norito Katoh
      Pages 289-299
    4. Yukihiro Ohya
      Pages 301-310
    5. Ken Igawa, Hiroo Yokozeki
      Pages 329-342
  10. Complications

    1. Front Matter
      Pages 343-343
    2. Takahiro Tokunaga, Shigeharu Fujieda
      Pages 345-354
    3. Reiko Kishikawa, Akiko Sugiyama
      Pages 355-366
  11. Clinical Questions

    1. Front Matter
      Pages 367-367
  12. Ryoji Tanei
    Pages E1-E1

About this book


This comprehensive guide offers a state-of-the-art overview of basic and clinical aspects of atopic dermatitis (AD).

The name "atopic dermatitis" was first used in 1933, and Drs. Lewis Webb Hill and Marion B. Sulzberger presented their report "Evolution of atopic dermatitis" in 1935. Their observations accurately forecasted the contemporary issues in the management of the condition, such as the conclusions that should be drawn from our understanding of the pathogenesis of AD, and the use of steroids as the main treatment. Several aggravating factors have recently been identified, and these also need to be addressed.

In this context, the expert contributors to this book describe and discuss the evolution of atopic dermatology from Sulzberger’s era to the present day, including clinical manifestations, etiopathology and treatment. In addition, it explores skin care intervention, the role of microbiom and GWAS studies, and presents unique, previously unpublished cohort studies.

It provides insights into the dynamic changes in AD since Sulzberger introduced topical steroids for its treatment. It is a valuable resource for dermatologists, medical practitioners and researchers who are interested in atopic dermatology.


Steroid Skin care intervention Microbiom GWAS studies Cytokine

Editors and affiliations

  • Ichiro Katayama
    • 1
  • Hiroyuki Murota
    • 2
  • Takahiro Satoh
    • 3
  1. 1.Department of Dermatology, Integrated MedicineGraduate School of Medicine, Osaka UniversitySuitaJapan
  2. 2.Department of Dermatology, Integrated MedicineGraduate School of Medicine, Osaka UniversitySuitaJapan
  3. 3.Department of DermatologyNational Defense Medical CollegeTokorosazawaJapan

Bibliographic information

  • DOI
  • Copyright Information Springer Nature Singapore Pte Ltd. 2018
  • Publisher Name Springer, Singapore
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-981-10-5540-9
  • Online ISBN 978-981-10-5541-6
  • Buy this book on publisher's site