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  • © 2016

Non-coding RNA and the Reproductive System

Editors:

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  • Presents a unique collection of the latest advances in identifying and understanding the role of non-coding RNA in sexual differentiation

  • Covers both the role of non-coding RNAs in the development of the reproductive system and their implication in disease, such as breast and prostate cancer

  • Comprehensive coverage of the function of non-coding RNAs in the development and disease of the reproductive system forms an invaluable basis for further functional studies

  • Written by international experts in their field who provide the very latest details on non-coding RNA function

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 886)

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USD 129.00
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  • ISBN: 978-94-017-7417-8
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  • Tax calculation will be finalised during checkout
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USD 169.99
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Table of contents (9 chapters)

  1. Front Matter

    Pages i-vii
  2. The Reproductive System

    • Andrew Pask
    Pages 1-12
  3. Non-coding RNAs: An Introduction

    • Jennifer X. Yang, Raphael H. Rastetter, Dagmar Wilhelm
    Pages 13-32
  4. How Many Non-coding RNAs Does It Take to Compensate Male/Female Genetic Imbalance?

    • Jean-François Ouimette, Claire Rougeulle
    Pages 33-49
  5. The piRNA Pathway Guards the Germline Genome Against Transposable Elements

    • Katalin Fejes Tóth, Dubravka Pezic, Evelyn Stuwe, Alexandre Webster
    Pages 51-77
  6. Non-coding RNA in Ovarian Development and Disease

    • J. Browning Fitzgerald, Jitu George, Lane K. Christenson
    Pages 79-93
  7. Non-coding RNA in Spermatogenesis and Epididymal Maturation

    • J. E. Holt, S. J. Stanger, B. Nixon, E. A. McLaughlin
    Pages 95-120
  8. Non-coding RNAs in Mammary Gland Development and Disease

    • Gurveen K. Sandhu, Michael J. G. Milevskiy, Wesley Wilson, Annette M. Shewan, Melissa A. Brown
    Pages 121-153
  9. Back Matter

    Pages 191-198

About this book

This book provides an overview of the role and function of regulatory RNAs that lack protein-coding potential in key reproductive tissues. This includes the role of small interfering RNAs (siRNAs), microRNAs (miRNAs), PIWI-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs) and long non-coding RNAs (lncRNAs). Through clear, detailed and comprehensive debate, international leading experts discuss the role these novel regulators in normal development of sexual dimorphisms, including the differentiation of ovaries and testes, the genital tract including prostate, epididymis and uterus, as well as mammary glands. In addition, particular attention is paid on their role in pathophysiological processes within the reproductive tract.

The power of next generation sequencing has proved to be an invaluable tool to discover new non-coding RNAs. While the identification of non-coding RNA is relatively easy, analysing their function represents still a challenge today. In this book, authors present historical and conceptual background information, highlight the ways in which non-coding RNAs function is analysed and present their vision of the future research in their key research area.

Keywords

  • diseases of the reproductive system
  • gene regulation
  • non-coding RNA
  • reproduction
  • sex differentiation

Editors and Affiliations

  • Department of Anatomy and Neuroscience, The University of Melbourne Department of Anatomy and Neuroscience, Parkville, Australia

    Dagmar Wilhelm

  • School of BioSciences, The University of Melbourne School of BioSciences, Melbourne, Australia

    Pascal Bernard

Bibliographic Information

Buying options

eBook
USD 129.00
Price excludes VAT (USA)
  • ISBN: 978-94-017-7417-8
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Softcover Book
USD 169.99
Price excludes VAT (USA)
Hardcover Book
USD 169.99
Price excludes VAT (USA)