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© 2015

Dendritic Cells: Biophysics, Tumor Microenvironment and Chinese Traditional Medicine

Book

Part of the SpringerBriefs in Biochemistry and Molecular Biology book series (BRIEFSBIOCHEM)

Table of contents

  1. Front Matter
    Pages i-vii
  2. Zhu Zeng, Xiaofeng Xu, Dan Chen
    Pages 1-4
  3. Zhu Zeng, Xiaofeng Xu, Dan Chen
    Pages 5-10
  4. Zhu Zeng, Xiaofeng Xu, Dan Chen
    Pages 25-53
  5. Zhu Zeng, Xiaofeng Xu, Dan Chen
    Pages 65-66

About this book

Introduction

In this book, the authors discuss the biophysical characteristics of Dendritic cells (DCs) at various differentiation stages and in tumor microenvironments in detail. A type of Chinese traditional herb, which can improve the biophysical and microrheological properties of DCs, is also introduced. DCs are potent and specialized antigen-presenting cells that play a crucial role in initiating and amplifying both the innate and adaptive immune responses. The biophysical and microrheological characteristics of DCs are important for their motility and normal immune function. In tumor microenvironments, the motility and immune functions of DCs are impaired, but the mechanisms are largely unknown. This book offers researchers a comprehensive and deep insight into the biophysical characteristics of DCs and may also help to improve the efficiency of anti-tumor therapy based on DCs.   

 

Keywords

biophysics dendritic cells immune escape mechanisms of tumor cells microrheology motility

Authors and affiliations

  1. 1.School of Biology and EngineeringGuizhou Medical UniversityGuiyangChina
  2. 2.Laboratory MedicineBeijing Tongren Hospital Capital Medical UniversityBeijingChina
  3. 3.Department of PharmacologyTianjin Medical University, School of Basic Medical SciencesTianjinChina

About the authors

Zhu Zeng is a professor of the Department of Biotechnology, and the vice president of the School of Basic Medical Sciences, Guiyang Medical College. He was awarded as the distinguished young science and technology scholars of Guizhou Province in 2011. Since 2000, his main research interests focused on biophysical characteristics of dendritic cells. 
Xiaofeng Xu is a doctor in the department of Laboratory Medicine, Beijing Tongren Hospital, Capital Medical University. Her research interests focused on biophysical characteristics of dendritic cells. 
Dan Chen is a lecturer of the Department of Pharmacology, School of Basic Medical Sciences, Tianjin Medical University. Her main research interests focused on the effects of traditional Chinese medicine on tumor biological behaviors.

Bibliographic information