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Intercellular Communication in Cancer

  • Mustapha Kandouz

Table of contents

  1. Front Matter
    Pages i-viii
  2. Jessian L. Munoz, Vivian Rodriguez-Cruz, Pranela Rameshwar
    Pages 43-51
  3. Marjolaine A. Pelissier-Rota, Nicolas T. Chartier, Muriel R. Jacquier-Sarlin
    Pages 53-149
  4. Ala-Eddin Al Moustafa, Amber Yasmeen
    Pages 169-187
  5. Yuan Hang Cao, Krikor Bijian, Maisa I. Alkailani, Moulay A. Alaoui-Jamali
    Pages 189-200
  6. George E. Parris
    Pages 227-254
  7. Mohamed Amessou, Mustapha Kandouz
    Pages 255-286
  8. Harini Krishnan, Gary S. Goldberg
    Pages 297-342
  9. Back Matter
    Pages 363-366

About this book

Introduction

Cells are by nature compelled to live in groups. They develop dependence over signaling cues received from their microenvironment, in particular from other cells, whether of their own “kind” or of a different type. Therefore, communicating with these cells is a critical aspect of their behavior and fate, as they live and die normally or as they undergo disease-related pathological changes, with dramatic repercussions.

In this book, we have asked expert researchers in the field of Intercellular Communication in Cancer to provide chapters on different aspects of interaction between neighboring cells, in the context of cancer diseases. We have specifically focused our efforts on membrane-to-membrane contact-based rather than growth factors-mediated modes of intercellular communications.

The contributing authors provide an extensive overview of their respective area of specialization, with an in-depth discussion of the molecular mechanisms of cell-cell interactions, the impact on tumor progression and response to therapies, as well as the cancer diagnostic value of this scientific information.

This book aims to introduce essential aspects of the normal and pathological cellular fate and homeostasis to both scientists and clinicians, and also to provide established researchers with an update on the novelties and future directions this expanding field is witnessing.

Keywords

Cancer Cell junctions Homeostasis Intercellular communication Therapy

Editors and affiliations

  • Mustapha Kandouz
    • 1
  1. 1.Department of PathologyWayne State University School of MedicineDetroitUSA

Bibliographic information