Molecular Farming of Plants and Animals for Human and Veterinary Medicine

1. Front Matter

   Pages i-xix

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2. Tobacco, a Platform for the Production of Recombinant Proteins

   • R. T. Rymerson, R. Menassa, J. E. Brandle

   Pages 1-31

3. Alfalfa: An Efficient Bioreactor for Continuous Recombinant Protein Production

   • M.-A. D’Aoust, U. Busse, M. Martel, L. Faye, D. Levesque, L.-P. Vezina

   Pages 33-47

4. The Use of Viral Vectors for the Production of Recombinant Proteins in Plants

   • G. P. Lomonossoff

   Pages 49-71

5. Control of the N-Glycosylation of Therapeutic Glycoproteins Produced in Transgenic Plants: A New Challenge for Glycobiologists

   • P. Lerouge, M. Bardor, S. Pagny, V. Gomord, A-C. Fitchette, L. Faye

   Pages 73-109

6. Production and Commercialization of Biopharmaceuticals from Milk

   • M. G. A. Peters, M. F. Brink

   Pages 111-125

7. A Seed-Derived Oral Subunit Vaccine for Human Cytomegalovirus

   • E. S. Tackaberry, K. E. Wright, A. K. Dudani, I. Altosaar, P. R. Ganz

   Pages 127-153

8. Use of Plant Virus-Based Expression Systems for the Production of HIV Vaccines

   • G. G. Zhang

   Pages 155-177

9. Suppression of Autoimmune Diabetes by the Use of Transgenic Plants Expressing Autoantigens to Induce Oral Tolerance

   • S. Ma, A. M. Jevnikar

   Pages 179-196

10. The Production and Delivery of Therapeutic Peptides in Plants

    • L. Erickson, W-J. Yu, J. Zhang, C. F. M. deLange, B. McBride, S. Du

    Pages 197-222

11. An Oral Vaccine in Maize Protects Against Transmissible Gastroenteritis Virus in Swine

    • J. Jilka

    Pages 223-236

12. Production of Antibodies in Alfalfa (Medicago Sativa)

    • U. Busse, V. Levee, S. Trepanier, L. Vezina

    Pages 237-257

13. The Production of Recombinant Antibodies in Plants and Plant Cells

    • R. Fischer, N. Emans, S. Schillberg

    Pages 259-285

14. Immunotherapeutic Potential of Antibodies Produced in Chicken Eggs

    • Y. Mine, J. Kovacs-Nolan

    Pages 287-317

15. The Production of Recombinant Cytokines in Plants

    • R. Menassa, A. Jevnikar, J. Brandle

    Pages 319-338

16. Edible Vaccines in Plants for Livestock Pathogens

    • L. Erickson, W-J. Yu, T. Tuboly, E. Nagy, A. Bailey, J. Zhang et al.

    Pages 339-367

17. Back Matter

    Pages 369-374

    PDF

Molecular farming has been hailed as the "third wave" of genetically-modified organisms produced through biotechnology for the bio-based economy of the future. Unlike products of the first wave, such as herbicide resistant crop plants, which were perceived to benefit only the farmers who used them and the agrochemical companies who developed them, products of molecular farming are designed specifically for the benefit of the consumer. Such products could be purified from food or non-food organisms for a range of applications in industry, as well as animal and human health. Alternatively, the products of this technology could be consumed more directly in some edible format, such as milk, eggs, fruits or vegetables. There is a rapidly-growing interest Qn the part of the public as well as in the medical community in the role food plays in health, especially in the immunophysiological impact of food over and above the role of basic nutrition.

• Bur
• Enteritis
• Expression
• Nager
• Pathogen
• Protein
• Seed
• biology
• biotechnology
• genetics
• regulation
• transgen

• Department of Plant Agriculture, University of Guelph, Geulph, Canada

  L. Erickson

• Syngenta Biotechnology Inc., Research Triangle Park, USA

  W.-J. Yu

• Research Branch, Agriculture and Agri-Food Canada, London, Canada

  J. Brandle, R. Rymerson

Policies and ethics