Spinal Cord Injury

  • N. Eric Naftchi

Table of contents

  1. Front Matter
    Pages i-xviii
  2. Molecular Mechanisms of Acute Traumatic Spinal Cord Injury

    1. Front Matter
      Pages 1-1
    2. N. T. Pay, A. E. George, M. V. Benjamin, R. T. Bergeron, J. P. Lin, I. Kricheff
      Pages 15-28
    3. H. B. Demopoulos, E. S. Flamm, M. L. Seligman, J. Ransohoff, N. E. Naftchi
      Pages 45-64
  3. Sequelae of Spinal Cord Injury: Possible Mechanisms of Spasticity and Pain Perception

  4. Hemodynamic Changes During Autonomic Dysreflexia

  5. Bone Mineral and Matrix Changes Following Spinal Cord Injury: Possible Modes of Treatment

    1. Front Matter
      Pages 177-177
    2. N. E. Naftchi, A. T. Viau, G. H. Sell, E. W. Lowman
      Pages 205-217
    3. J. Claus-Walker, J. Singh, N. DiFerrante
      Pages 219-223
  6. Renal and Urinary Bladder Physiology

    1. Front Matter
      Pages 225-225
    2. K. T. Ragnarsson, M. Krebs, N. E. Naftchi, M. Demeny, G. H. Sell, E. W. Lowman et al.
      Pages 233-240
  7. Hormonal and Behavioral Aspects of Spinal Cord Research

    1. Front Matter
      Pages 241-241
    2. N. E. Naftchi, A. T. Viau, G. H. Sell, E. W. Lowman
      Pages 243-252
  8. Back Matter
    Pages 267-269

About this book


We shall not, and those who come after us must not, accept the goals that were not reached yesterday as unsurmountable today or tomorrow. We will strive to render the world of the paralyzed-on-wheels but a transitory stop, and settle for nothing short of optimal recovery. N. Eric Naftchi In man, the process of "encephalization" culminates in almost complete control of the brain over the lower centers. Transection of the spinal cord severs the extensions of its nerve fiber tracts running to and from various brain centers. Although there is some confusion on the meaning of spinal shock, it is supposed to last from two to three weeks or longer in man, compared with less than a few minutes in the frog. This is a testimony to the complexity of the suprasegmental control in higher animals. Since the brain exerts its control over the internal environment through several monoamine, amino acids, and peptide neurotransmitters, it should not be surprising if the metabolism of these transmitters is found to be drastically altered along with other physical and metabolic dysfunctions which ensue following the spinal cord section. In spite of the major strides in rehabilitation of traumatic spinal cord injury, our knowledge of the etiology underlying the diverse neurophysiologic derangements remains limited. For instance, we are just becoming aware of some of the changes in the "milieu interieur.


bone brain catecholamines clinical trial clonidine pathogenesis perception rehabilitation spinal cord trauma

Editors and affiliations

  • N. Eric Naftchi
    • 1
  1. 1.Institute of Rehabilitation MedicineNew York University Medical CenterUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media B.V. 1982
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-94-011-6307-1
  • Online ISBN 978-94-011-6305-7
  • Buy this book on publisher's site