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Advanced Bioactive Compounds Countering the Effects of Radiological, Chemical and Biological Agents

Strategies to Counter Biological Damage

  • Conference proceedings
  • © 2013


  • Unique approach to use nutraceuticals to protect against radiation-induced injury
  • Mechanisms of oxidative damage
  • A more comprehensive discussion of mechanisms of damage of a wide variety of man-made environmental toxins that exist currently and a unique compilation of strategies to negate the influence of these toxins

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About this book

The probability for exposure to damaging radiation, toxic chemicals in the environment and adverse biological agents has increased exponentially today. The more frequent and faster travel that we experience today also escalates the risk of contraction and transmission of potentially deadly infections. This has created a very real and escalating risk for injuries and deaths. This is accentuated in the military and medical staff that is more frequently exposed to radiological, chemical,  and  biological  agents  in their  normal working  environment. Understanding the mechanisms whereby these toxic agents inflict damage to our bodies is essential to prepare us for these challenges.Much of the damage is inflicted through the generation of free radicals and non-radical oxidants which then act through oxidative mechanisms to injury the body. This volume will discuss the damage caused by these radiological, chemical, and biological environmental stressors, the mechanisms through which the damage can occur and the novel strategies that can be used to reduce the injury inflicted by these toxic compounds. Using basic and clinical research approaches, the contents of this book  discuss  new  ideas  for  the  development  of  bioactive  products  and  environmental approaches to lessen or negate the biological damage inflicted by thesenoxious compounds.

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Table of contents (25 papers)

  1. Tissue Damage due to Radiological Agents

  2. Preventing the Harmful Health Effects of Biological Agents

  3. Bioactive Compounds from Natural Sources for Prophylaxis and Treatment of the Effects of Radiological, Chemical and Biological Agents


From the reviews:

“This book concerns itself with nonconventional means of preventing, reversing and rehabilitating living systems that have been subjected to a variety of environmental stressors. … the primary audience might appear to be basic scientists. … the book should find an audience among clinicians of all types who should consider these findings. … It covers both basic and clinical research approaches, developing new ideas for bioactive product development as well as environmental approaches to lessen or negate the biological damage already inflicted.” (J. Thomas Pierce, Doody’s Book Reviews, November, 2013)

Editors and Affiliations

  • St. Boniface Hospital Research Centre, Winnipeg, Canada

    Grant N. Pierce, Alexander Omelchenko

  • , Division of Health and Rehabilitation, Crimean State Humanitarian University, Yalta, Crimea, Ukraine

    Volodymyr I. Mizin

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