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The Chaperonopathies

Diseases with Defective Molecular Chaperones

  • Alberto J.L. Macario
  • Everly Conway de Macario
  • Francesco Cappello

Part of the SpringerBriefs in Biochemistry and Molecular Biology book series (BRIEFSBIOCHEM)

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Alberto J.L Macario, Everly Conway de Macario, Francesco Cappello
    Pages 1-14
  3. Alberto J.L Macario, Everly Conway de Macario, Francesco Cappello
    Pages 15-33
  4. Alberto J.L Macario, Everly Conway de Macario, Francesco Cappello
    Pages 35-42
  5. Alberto J.L Macario, Everly Conway de Macario, Francesco Cappello
    Pages 43-62
  6. Alberto J.L Macario, Everly Conway de Macario, Francesco Cappello
    Pages 63-69
  7. Alberto J.L Macario, Everly Conway de Macario, Francesco Cappello
    Pages 71-74
  8. Alberto J.L Macario, Everly Conway de Macario, Francesco Cappello
    Pages 75-106
  9. Alberto J.L Macario, Everly Conway de Macario, Francesco Cappello
    Pages 107-108
  10. Alberto J.L Macario, Everly Conway de Macario, Francesco Cappello
    Pages 109-116

About this book

Introduction

Memory lapses and occasional incoherent behavior, or intestinal cramps with diarrhea, or protracted cough with low fever, or cardiovascular syndromes, or changes in the pattern of movement of the lower limps, can be signs of an incipient chaperonopathy. Yet many physicians do not know this. Most health care professionals are unfamiliar with chaperonopathies. Clinicians do not look for them because they are unaware of them. Pathologists and clinical biochemists are unprepared to test specimens to detect chaperonopathies. Despite the large amount of information available in the literature, textbooks tend to ignore chaperonopathies. Because of the lack of systematic information in textbooks and courses, chaperonopathies are invisible to practitioners and clinical researchers. This book aims to correct this situation by providing pertinent information in an orderly manner so as to prompt the reader to look for chaperonopathies in patients and seek more information about them. The book serves as an alert signal and as a primer.

Keywords

Chaperoning System Chaperonopathies Chaperonopathy Heat Shock Proteins Molecular Chaperones Stress

Authors and affiliations

  • Alberto J.L. Macario
    • 1
  • Everly Conway de Macario
    • 2
  • Francesco Cappello
    • 3
  1. 1.School of Medicine, Dept. of Microbiology and ImmunologyUniversity of MarylandBaltimoreUSA
  2. 2.Biotechnology Inst., Department of Microbiology and ImmunologUniversity of MarylandBaltimoreUSA
  3. 3., Department of Experimental BiomedicineUniversity of PalermoPalermoItaly

Bibliographic information

  • DOI https://doi.org/10.1007/978-94-007-4667-1
  • Copyright Information The Author(s) 2013
  • Publisher Name Springer, Dordrecht
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-94-007-4666-4
  • Online ISBN 978-94-007-4667-1
  • Series Print ISSN 2211-9353
  • Series Online ISSN 2211-9361
  • Buy this book on publisher's site