Epigenetics: Development and Disease

  • Tapas K. Kundu

Part of the Subcellular Biochemistry book series (SCBI, volume 61)

Table of contents

  1. Front Matter
    Pages i-xxvi
  2. Epigenetics and Evolution

    1. Front Matter
      Pages 1-1
    2. Sujata Kumari, Amrutha Swaminathan, Snehajyoti Chatterjee, Parijat Senapati, Ramachandran Boopathi, Tapas K. Kundu
      Pages 3-35
    3. Benjamin Audit, Lamia Zaghloul, Antoine Baker, Alain Arneodo, Chun-Long Chen, Yves d’Aubenton-Carafa et al.
      Pages 57-80
    4. Ritesh Kumar, Desirazu N. Rao
      Pages 81-102
  3. Developmental Epigenetics

    1. Front Matter
      Pages 103-103
    2. Oliver Meikar, Matteo Da Ros, Noora Kotaja
      Pages 119-138
    3. Narendra Bharathy, Belinda Mei Tze Ling, Reshma Taneja
      Pages 139-150
    4. Asmitha Lazarus, Kushal Kr. Banerjee, Ullas Kolthur-Seetharam
      Pages 151-176
    5. Navneet K. Matharu, Vasanthi Dasari, Rakesh K. Mishra
      Pages 177-207
  4. Epigenetics and Transcription Regulation

    1. Front Matter
      Pages 209-209
    2. Sarah J. Goodfellow, Joost C. B. M. Zomerdijk
      Pages 211-236
    3. Cindy Law, Peter Cheung
      Pages 319-341
    4. Karthigeyan Dhanasekaran, Sujata Kumari, Chandrasekhar Kanduri
      Pages 343-372
    5. Benoît Moindrot, Philippe Bouvet, Fabien Mongelard
      Pages 373-396

About this book

Introduction

Epigenetics is the phenomenon which fine tunes the processes associated with life, beyond that which is specified by the sequence of the genetic material; DNA. The covalent modification of DNA, DNA associated histones, several non histone proteins as well as non coding RNA coherently operate to establish the epigenetic regulation of gene expression in physiological and pathophysiological conditions.

This volume presents contributions from worldwide experts presenting their research and findings, including: the evolution of epigenetic machineries from archaea to higher eukaryotes; role of epigenetics in development and transcription regulation; epigenetic landscape of human disease; a chemical biology approach to understanding epigenetic phenomena; exploration of different small molecules as epigenetic therapies.

This volume is aimed at students and researchers of chromatin biology and epigenetics and will also be of interest to a broader pharmaceutical audience.

Keywords

Cancer and diabetes Chromatin dynamics Epigenetic therapy Gene expression Stem cell differentiation and development

Editors and affiliations

  • Tapas K. Kundu
    • 1
  1. 1.Advanced Scientific Research, Molecular Biology and Genetics UnitJawaharlal Nehru Centre forBangaloreIndia

Bibliographic information

  • DOI https://doi.org/10.1007/978-94-007-4525-4
  • Copyright Information Springer Science+Business Media Dordrecht 2013
  • Publisher Name Springer, Dordrecht
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-94-007-4524-7
  • Online ISBN 978-94-007-4525-4
  • Series Print ISSN 0306-0225
  • About this book