Overview
- Concise review of current state-of-the-art in research on respiratory complex I
- The first book entirely devoted to complex I, a central enzyme in bioenergetics
- Recent breakthroughs in structure elucidation finally allow some understanding of the mechanism
- Mutations leading to common and severe human disorders are discussed
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Keywords
Table of contents (12 chapters)
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Mutations in complex I subunits and medical implications
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Subunit composition and assembly of mitochondrial complex I
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Supercomplexes in mitochondria
Editors and Affiliations
Bibliographic Information
Book Title: A Structural Perspective on Respiratory Complex I
Book Subtitle: Structure and Function of NADH:ubiquinone oxidoreductase
Editors: Leonid Sazanov
DOI: https://doi.org/10.1007/978-94-007-4138-6
Publisher: Springer Dordrecht
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Science+Business Media Dordrecht 2012
Hardcover ISBN: 978-94-007-4137-9Published: 16 May 2012
Softcover ISBN: 978-94-017-8334-7Published: 11 June 2014
eBook ISBN: 978-94-007-4138-6Published: 11 May 2012
Edition Number: 1
Number of Pages: X, 286
Topics: Biomedicine general, Biochemistry, general, Protein Structure, Membrane Biology, Molecular Medicine