© 2012

Stem Cells and Cancer Stem Cells, Volume 5

Therapeutic Applications in Disease and Injury

  • M.A. Hayat

Part of the Stem Cells and Cancer Stem Cells book series (STEM, volume 5)

Table of contents

  1. Front Matter
    Pages i-xix
  2. Cancer Stem Cells

    1. Front Matter
      Pages 1-1
    2. Anna Pastò, Alberto Amadori, Stefano Indraccolo
      Pages 3-11
    3. Ryan Nitta, Ning Go, Ariel A. Avilion, Immanual Joseph
      Pages 13-24
    4. Marcello Maugeri-Saccà, Ann Zeuner
      Pages 25-36
    5. Veronica Catalano, Antonina Benfante, Pietro Mancuso, Francesco Dieli, Giorgio Stassi, Matilde Todaro
      Pages 37-43
  3. Tissue Injury

    1. Front Matter
      Pages 45-45
    2. Júlia Teixeira Oliveira, Fernanda Martins Almeida, Ana Maria Blanco Martinez
      Pages 47-58
    3. Tatsuki Itoh, Motohiro Imano, Shozo Nishida, Masahiro Tsubaki, Shigeo Hashimoto, Akihiko Ito et al.
      Pages 59-72
    4. Cindy T. J. van Velthoven, Annemieke Kavelaars, Cobi J. Heijnen
      Pages 73-83
  4. Cardiovascular Applications

    1. Front Matter
      Pages 93-93
    2. Mehmet Tokaç, Tahsin Murad Aktan
      Pages 103-108
    3. Daria Nurzynska, Franca Di Meglio, Stefania Montagnani, Clotilde Castaldo
      Pages 109-115
    4. María Gutiérrez-Fernández, Berta Rodríguez-Frutos, Blanca Fuentes, Exuperio Díez-Tejedor
      Pages 117-127
  5. Bone Diseases

    1. Front Matter
      Pages 129-129
    2. Zou Xiao Hui, Shen Wei Liang, Boon Chin Heng, Ouyang Hong Wei
      Pages 131-135
    3. Pill-Hoon Choung, Young-Min Ji, Han-Wool Choung
      Pages 149-159

About this book


The fifth volume in the essential series on stem cell biology provides a detailed explanation of the mechanisms of self-renewing cancer stem cells, as well as their ability to generate the heterogeneous lineages of cancer cells that comprise tumors. It explores the unique resistance of cancer stem cells to conventional chemotherapy techniques able to kill a tumor’s constituent cells. The contents also include a discussion of the myriad applications of a selection of stem cells in treating disease and tissue injury. The cells singled out include human mesenchymal, arterial, neural, cardiac, dental, limbal, and hematopoietic stem cells. The therapeutic utility of uniquely adaptable human embryonic stem cells, able to generate any human cell type, is explored in depth. The volume looks at their uses in tissue engineering and regenerative medicine, as well as pharmacological, toxicological, and cell differentiation research. It also sheds light on the processes by which embryonic stem cells begin to differentiate by aggregating into more complex embryoid bodies. With additional material on targeting self-renewal pathways in cancer stem cells, the use of mesenchymal stem cells in treating ischemic brain injury, and the phenomenon of neural stem cell proliferation around traumatic brain injuries, this richly diverse and hugely informative book is a powerful tool for deepening professional expertise among researchers and practitioners in this field.


Cancer therapy Dental implants Neurosurgery Tissue repair Treatment of eye disorders

Editors and affiliations

  • M.A. Hayat
    • 1
  1. 1., Kean UniversityRoom 213, Library buildingUnionUSA

Bibliographic information