Overview
- first comprehensive compilation of expert reviews on tumor stroma and its role in tumor biology important for basic and clinical cancer researchers
- Highlighting promising new targets for cancer therapy
- novel textbook for teaching tumor biology to graduate students
- Includes supplementary material: sn.pub/extras
Part of the book series: The Tumor Microenvironment (TTME, volume 4)
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About this book
During the last 20 years it has become increasingly clear that the tumor micro-environment, the tumor stroma with its cellular end extracellular components, plays an crucial role in regulating tumor growth and progression. This book on “Tumor-associated fibroblasts and their matrix” as part of the series on “Tumor-Microenvironment” is the first comprehensive discussion of these two main players of the tumor microenvironment. The best experts in this new area of tumor research and therapy review the role of these major components in the tumor stroma in the process of tumor development and progression. They discuss their interaction with other players such as blood vessels and immune cells, and show novel perspectives for tumor therapy. This compilation of excellent contributions of the best known experts in this important field in cancer research and therapy is a must for all scientists engaged in basic and clinical research. Increasing evidence of successful targeting of both cellular and matrix components in tumor therapy renders this book of particular interest for scientists engaged in pharmaceutical industry searching for new components for cancer therapy.
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Keywords
Table of contents (22 chapters)
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Front Matter
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The Tumor Microenvironment
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Front Matter
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Stromal Cell Diversity
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Front Matter
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Tumor Modulating-Fibroblast Interactions
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Front Matter
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Editors and Affiliations
Bibliographic Information
Book Title: Tumor-Associated Fibroblasts and their Matrix
Editors: Margareta M. Mueller, Norbert E. Fusenig
Series Title: The Tumor Microenvironment
DOI: https://doi.org/10.1007/978-94-007-0659-0
Publisher: Springer Dordrecht
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Science+Business Media B.V. 2011
Hardcover ISBN: 978-94-007-0658-3Published: 28 July 2011
Softcover ISBN: 978-94-007-3767-9Published: 27 November 2013
eBook ISBN: 978-94-007-0659-0Published: 28 July 2011
Edition Number: 1
Number of Pages: XVI, 456
Topics: Cancer Research, Biomedicine general, Oncology