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  • Conference proceedings
  • Open Access
  • © 2015

Innovative Medicine

Basic Research and Development


(view affiliations)
  • Covers the basic, translational, and new technology of medical research

  • Broadens the understanding of innovative medicine

  • Is written by leading scientists in medical research

  • Includes supplementary material:

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Softcover Book
USD 59.99
Price excludes VAT (USA)
Hardcover Book
USD 59.99
Price excludes VAT (USA)

Table of contents (27 papers)

  1. Translational Research for Innovative Medicine

    1. Autophagic Cell Death and Cancer Chemotherapeutics

      • Shigeomi Shimizu
      Pages 219-226Open Access
    2. Adrenomedullin as a Potential Therapeutic Agent for Refractory Ulcerative Colitis

      • Kazuo Kitamura, Shinya Ashizuka, Haruhiko Inatsu, Toshihiro Kita
      Pages 227-240Open Access
    3. RNA Activation

      • X. Y. Zhao, J. Voutila, Nagy A. Habib, Vikash Reebye
      Pages 241-249Open Access
  2. New Technology for Innovative Medicine

    1. Front Matter

      Pages 251-251
    2. Development of a New In Vivo Optical Probe for Biological Diagnosis and Therapy

      • Michitaka Ozaki, Takeaki Ozawa, Yuma Yamada
      Pages 265-279Open Access
    3. Introduction of Mesenchymal Stem Cells for Liver Surgery (Hepatectomy and Transplantation)

      • Shinji Uemoto, Yasuhiro Fujimoto, Takumi Teratani, Hiroyuki Kanazawa, Junji Iwasaki, Zhao Xiangdong et al.
      Pages 281-293Open Access
    4. TGF-β LAP Degradation Products, a Novel Biomarker and Promising Therapeutic Target for Liver Fibrogenesis

      • Mitsuko Hara, Tomokazu Matsuura, Soichi Kojima
      Pages 317-325Open Access
    5. Cell-Based Regenerative Therapy for Liver Disease

      • Kenichi Horisawa, Atsushi Suzuki
      Pages 327-339Open Access

About this book

This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.


  • Cancer
  • Clinical application
  • Metabolism
  • Stem cell
  • Translational research

Editors and Affiliations

  • Medical Innovation Center, Kyoto University Graduate School of Medicine, Kyoto, Japan

    Kazuwa Nakao

  • Department of Immunology & Cell Biology, Kyoto University Graduate School of Medicine, Kyoto, Japan

    Nagahiro Minato

  • Department of Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan

    Shinji Uemoto

Bibliographic Information

  • Book Title: Innovative Medicine

  • Book Subtitle: Basic Research and Development

  • Editors: Kazuwa Nakao, Nagahiro Minato, Shinji Uemoto

  • DOI:

  • Publisher: Springer Tokyo

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s) 2015

  • License: CC BY-NC

  • Hardcover ISBN: 978-4-431-55650-3

  • Softcover ISBN: 978-4-431-56246-7

  • eBook ISBN: 978-4-431-55651-0

  • Edition Number: 1

  • Number of Pages: IX, 339

  • Topics: Biomedical Research, Immunology, Cell Biology

Buying options

Softcover Book
USD 59.99
Price excludes VAT (USA)
Hardcover Book
USD 59.99
Price excludes VAT (USA)