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Ruminant Pestivirus Infections

Virology, Pathogenesis, and Perspectives of Prophylaxis

  • Conference proceedings
  • © 1991


Part of the book series: Archives of Virology. Supplementa (ARCHIVES SUPPL, volume 3)

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About this book

Findings concerning various clinical manifestations in cattle and sheep have made it clear that pestivirus infections in ruminants have an economic impact similar to hog cholera. Early data justified the classification of pestiviruses as a genus of nonarthopod-borne togaviruses. Since pestiviruses are difficult to work with, progress in understanding the virus and disease gradually came to a standstill because conventional techniques failed to yield further insights. About ten years ago interest in pestivirology was revived by strong impulses of modern biotechnology and a breakthrough in pathogenesis research, i.e. in vitro translation of BVD viral proteins and the ex experimental reproduction of mucosal disease in cattle. In order to summarize and discuss these exciting developments, an international community of pestivirus researchers came together in June 1990 in Hannover (Federal Republic of Germany) for the Symposium "Ruminant Pestivirus Infections: Virology, Pathogenesis and Perspectives on Prophylaxis". This book is a selection of papers presented at this symposium.

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Table of contents (34 papers)

  1. Pestiviruses—taxonomic perspectives

  2. Molecular characterization of hog cholera virus

  3. Bovine viral diarrhea virus genomic organization

  4. Bovine viral diarrhea virus proteins and their antigenic analyses

  5. A “zinc finger-like” domain in the 54 KDA protein of several pestiviruses

  6. BVD monoclonal antibodies: relationship between viral protein specificity and viral strain specificity

  7. Correlation of bovine viral diarrhoea virus induced cytopathic effects with expression of a biotype-specific marker

  8. Cytopathogenicity of pestiviruses isolated post mortem from cattle

  9. Diaplacental infections with ruminant pestiviruses

  10. The pathways for bovine virus diarrhoea virus biotypes in the pathogenesis of disease

  11. Border disease of sheep— Aspects for diagnostic and epidemiologic consideration

  12. A study of some pathogenetic aspects of bovine viral diarrhea virus infection

  13. Distribution of antigen of noncytopathogenic and cytopathogenic bovine virus diarrhea virus biotypes in the intestinal tract of calves following experimental production of mucosal disease

  14. Clinical and virological observations of a mucosal disease outbreak with persistently-infected seropositive survivors

  15. Insertion of cellular sequences in the genome of bovine viral diarrhea virus

  16. Congenital curly haircoat as a symptom of persistent infection with bovine virus diarrhoea virus in calves

  17. Identification and production of pestivirus proteins for diagnostic and vaccination purposes

  18. Surveillance of cattle herds for bovine virus diarrhoea virus (BVDV)-infection using data on reproduction and calf mortality

  19. Flow cytometric detection of bovine viral diarrhoea virus

Editors and Affiliations

  • Tierärztliche Hochschule Hannover, Hannover, Federal Republic of Germany

    B. Liess

Bibliographic Information

  • Book Title: Ruminant Pestivirus Infections

  • Book Subtitle: Virology, Pathogenesis, and Perspectives of Prophylaxis

  • Editors: B. Liess, V. Moennig, J. Pohlenz, G. Trautwein

  • Series Title: Archives of Virology. Supplementa

  • DOI:

  • Publisher: Springer Vienna

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag/Wien 1991

  • Softcover ISBN: 978-3-211-82279-1Published: 23 September 1991

  • eBook ISBN: 978-3-7091-9153-8Published: 06 December 2012

  • Series ISSN: 0939-1983

  • Edition Number: 1

  • Number of Pages: VIII, 271

  • Number of Illustrations: 78 b/w illustrations

  • Topics: Virology, Agriculture, Forestry, Microbiology, Cell Biology, Immunology

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