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The Parvoviruses

  • Günter Siegl

Part of the Virology Monographs / Die Virusforschung in Einzeldarstellungen book series (VIROLOGY, volume 15)

Table of contents

  1. Front Matter
    Pages i-3
  2. Günter Siegl
    Pages 4-4
  3. Günter Siegl
    Pages 5-6
  4. Günter Siegl
    Pages 6-85
  5. Günter Siegl
    Pages 86-94
  6. Günter Siegl
    Pages 95-96
  7. Back Matter
    Pages 97-112

About this book

Introduction

I. Introduction Parvoviruses belong to the large group of viral agents of which virologists have become aware by chance in many biological materials due to the availabil­ ity of more sensitive isolation techniques and the extensive use of the electron microscope. In general, many of these viruses lacked the stimulating background of an infectious disease and, therefore, have fallen into oblivion already soon after discovery. In case of parvoviruses, however, interest has been maintained because of the circumstances under which most of them were isolated. A great number of parvoviruses has been recovered from tissues of tumor­ bearing animals, from cell-free filtrates of tumors, or from stable cell lines of tumor origin. These observations necessarily suggested the newly isolated viral agents of playing an important, yet unknown role in the induction and develop­ ment of cancer. On the other hand, further parvoviruses were found constantly associated with adenoviruses. It was the experimental analysis of the multiplica­ tion behaviour which then revealed that the association between parvoviruses and tumors or parvoviruses and adenoviruses originates from the basis of a cer­ tain genetic defectiveness. For some members of the group this may be overcome by cellular helper effects in rapidly growing tissues, for several others, however, by biochemical events in the simultaneously occurring replication of an adeno­ virus only. Additional points of view in favour of parvovirus research have arisen from experimental animal studies.

Keywords

Parvovirus Parvoviruskrankheit

Authors and affiliations

  • Günter Siegl
    • 1
  1. 1.Institute of Hygiene and Medical MicrobiologyUniversity of BernBernSwitzerland

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-7091-8430-1
  • Copyright Information Springer-Verlag Vienna 1976
  • Publisher Name Springer, Vienna
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-7091-8432-5
  • Online ISBN 978-3-7091-8430-1
  • Series Print ISSN 0083-6591
  • Buy this book on publisher's site