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Fortschritte der Chemie Organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products

  • C. W. J. Chang
  • I. Flament
  • J. A. Matson
  • T. Nishida
  • G. Ohloff
  • F. W. Wehrli
  • A. J. Weinheimer
  • W. Herz
  • H. Grisebach
  • G. W. Kirby

Table of contents

  1. Front Matter
    Pages I-VII
  2. A. J. Weinheimer, C. W. J. Chang, J. A. Matson
    Pages 285-387
  3. Back Matter
    Pages 389-428

About this book

Introduction

Since the late 1950's when proton n. m. r. spectroscopy was first used in organic natural products studies the technique has increasingly con­ of this important area of chemistry. tributed to the rapid advancement Although the potential utility of 13C n. m. r. was recognized very early, essentially no application of 13C n. m. r. appeared in the literature prior to 1966 and 95% of the existing data are less than five years old. The initially slow growth had its cause in inadequate instrumentation, insufficient sensitivity being the main obstacle. This situation drastically changed with the advent and commercial availability of broadband ex­ citation and Fourier transform methods, giving natural-abundance 13C n. m. r. and its numerous chemical applications a tremendous impetus. Today BC spectra can be recorded on sample quantities down to the submilligram level, which until recently even withstood proton n. m. r. Paralleling the development of experimental techniques considerable progress has also been made on an understanding of spectral parameters, in particular their stereochemical implications on natural products. Although the large majority of data present up to now deals with known structures, an adequate basis now exists which allows the chemist to use the technique for tackling real problems on unknown molecules.

Keywords

Naturstoffe carbon chemistry natural product natural products nuclear magnetic resonance research

Authors and affiliations

  • C. W. J. Chang
    • 1
  • I. Flament
    • 2
  • J. A. Matson
    • 3
  • T. Nishida
    • 4
  • G. Ohloff
    • 2
  • F. W. Wehrli
    • 5
  • A. J. Weinheimer
    • 3
  1. 1.Faculty of ChemistryUniversity of West FloridaPensacolaUSA
  2. 2.Laboratoire de RecherchesFirmenich SAGenève 8Switzerland
  3. 3.Department of Medicinal Chemistry and PharmacognosyUniversity of HoustonHoustonUSA
  4. 4.Research DepartmentSwedish Tobacco CompanyStockholm 17Sweden
  5. 5.Varian AGZugSwitzerland

Editors and affiliations

  • W. Herz
    • 1
  • H. Grisebach
    • 2
  • G. W. Kirby
    • 3
  1. 1.TallahasseeUSA
  2. 2.Freiburg i. Br.Germany
  3. 3.GlasgowUK

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-7091-3265-4
  • Copyright Information Springer-Verlag Vienna 1979
  • Publisher Name Springer, Vienna
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-7091-3267-8
  • Online ISBN 978-3-7091-3265-4
  • Series Print ISSN 0071-7886
  • Buy this book on publisher's site